Orexin receptor antagonist 2

Modify Date: 2025-08-26 19:08:24

Orexin receptor antagonist 2 Structure
Orexin receptor antagonist 2 structure
Common Name Orexin receptor antagonist 2
CAS Number 1457940-75-8 Molecular Weight 433.55
Density N/A Boiling Point N/A
Molecular Formula C25H31N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Orexin receptor antagonist 2


Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia[1].

 Names

Name Orexin receptor antagonist 2

 Orexin receptor antagonist 2 Biological Activity

Description Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia[1].
Related Catalog
References

[1]. Betschart C, et al. Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia. J Med Chem. 2013;56(19):7590-7607.

 Chemical & Physical Properties

Molecular Formula C25H31N5O2
Molecular Weight 433.55
InChIKey GKTSTVGKOKZFKP-UHFFFAOYSA-N
SMILES COc1ccc2[nH]cc(CN3CCCC4(CCN(c5nc(C)cc(C)n5)CC4)C3=O)c2c1
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