P2X7 receptor antagonist-3

Modify Date: 2025-08-25 11:58:41

P2X7 receptor antagonist-3 Structure
P2X7 receptor antagonist-3 structure
 Common Name P2X7 receptor antagonist-3
CAS Number 1627900-92-8 Molecular Weight 408.76
Density N/A Boiling Point N/A
Molecular Formula C17H12ClF3N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of P2X7 receptor antagonist-3


P2X7 receptor antagonist-3 is a potent P2X7 receptor antagonist with P2X7R IC50 values of 4.2 nM in humans and 6.8 nM in rats[1].

 Names

Name P2X7 receptor antagonist-3

 P2X7 receptor antagonist-3 Biological Activity

Description P2X7 receptor antagonist-3 is a potent P2X7 receptor antagonist with P2X7R IC50 values of 4.2 nM in humans and 6.8 nM in rats[1].
Related Catalog
Target

hP2X7R:4.2 nM (IC50)

rP2X7R:6.8 nM (IC50)

References

[1]. Brad M Savall, et al. Synthesis, SAR, and Pharmacological Characterization of Brain Penetrant P2X7 Receptor Antagonists. ACS Med Chem Lett. 2015 Apr 24;6(6):671-6.  

 Chemical & Physical Properties

Molecular Formula C17H12ClF3N6O
Molecular Weight 408.76
InChIKey BAXJLPUVDTUTBR-UHFFFAOYSA-N
SMILES O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(nnn2-c2ncccn2)C1
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Chemsrc provides P2X7 receptor antagonist-3(CAS#:1627900-92-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of P2X7 receptor antagonist-3 are included as well.>> amp version: P2X7 receptor antagonist-3

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