ALK5-IN-26

Modify Date: 2024-04-07 05:45:28

ALK5-IN-26 Structure
ALK5-IN-26 structure
Common Name ALK5-IN-26
CAS Number 2785430-82-0 Molecular Weight 444.51
Density N/A Boiling Point N/A
Molecular Formula C24H25FN8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ALK5-IN-26


ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 with an IC50 value ≤10 nM. ALK5-IN-26 can be used for the research of cancer[1].

 Names

Name ALK5-IN-26

 ALK5-IN-26 Biological Activity

Description ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 with an IC50 value ≤10 nM. ALK5-IN-26 can be used for the research of cancer[1].
Related Catalog
Target

IC50: ≤10 nM (ALK5)[1]

In Vitro ALK5-IN-26 (0-1 μM; 24 h) inhibits ALK5 with an IC50 value ≤10 nM, and shows selectivity of ALK2 IC50/ALK5 IC50 of a ratio <100[1].
References

[1]. Franz B, et al. ALK-5 INHIBITORS AND USES THEREOF. WO/2022/126133 A1. 2022.

 Chemical & Physical Properties

Molecular Formula C24H25FN8
Molecular Weight 444.51