Name | ALK5-IN-8 |
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Description | ALK5-IN-8 is a potent inhibitor of TGFβRI (ALK5). ALK5-IN-8 Inhibits the phosphorylation of ALK5 on its downstream signaling proteins (Smad2 or Smad3) by blocking the binding of TGFβRI to ligands, thereby affecting or blocking TGF-β signaling. ALK5-IN-8 has the potential for the research of various ALK5-mediated related diseases (extracted from patent WO2021190425A1, compound 1)[1]. |
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Related Catalog | |
References |
[1]. Zhiyong Yu, et al. Transforming growth factor-beta receptor inhibitor. Patent WO2021190425A1. |
Molecular Formula | C19H15FN4O2 |
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Molecular Weight | 350.35 |