ALK5-IN-8

Modify Date: 2023-01-16 19:08:21

ALK5-IN-8 Structure
ALK5-IN-8 structure
Common Name ALK5-IN-8
CAS Number 2705900-81-6 Molecular Weight 350.35
Density N/A Boiling Point N/A
Molecular Formula C19H15FN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ALK5-IN-8


ALK5-IN-8 is a potent inhibitor of TGFβRI (ALK5). ALK5-IN-8 Inhibits the phosphorylation of ALK5 on its downstream signaling proteins (Smad2 or Smad3) by blocking the binding of TGFβRI to ligands, thereby affecting or blocking TGF-β signaling. ALK5-IN-8 has the potential for the research of various ALK5-mediated related diseases (extracted from patent WO2021190425A1, compound 1)[1].

 Names

Name ALK5-IN-8

 ALK5-IN-8 Biological Activity

Description ALK5-IN-8 is a potent inhibitor of TGFβRI (ALK5). ALK5-IN-8 Inhibits the phosphorylation of ALK5 on its downstream signaling proteins (Smad2 or Smad3) by blocking the binding of TGFβRI to ligands, thereby affecting or blocking TGF-β signaling. ALK5-IN-8 has the potential for the research of various ALK5-mediated related diseases (extracted from patent WO2021190425A1, compound 1)[1].
Related Catalog
References

[1]. Zhiyong Yu, et al. Transforming growth factor-beta receptor inhibitor. Patent WO2021190425A1.

 Chemical & Physical Properties

Molecular Formula C19H15FN4O2
Molecular Weight 350.35
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: ALK5-IN-8
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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