ALK5-IN-9

Modify Date: 2024-04-10 17:43:28

ALK5-IN-9 structure	Common Name	ALK5-IN-9
	CAS Number	2489611-06-3	Molecular Weight	572.62
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₅F₃N₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ALK5-IN-9

ALK5-IN-9 (Compound 8h) is a potent and orally active inhibitor of TGFβRI (ALK5). ALK5-IN-9 inhibits ALK5 autophosphorylation and NIH3T3 cell activity with IC50 values of 25 nM and 74.6 nM, respectively. ALK5-IN-9 also shows favorable pharmacokinetic profile and ameliorated hERG inhibition. ALK5-IN-9 has the potential for the research of cancer disease[1].

Name	ALK5-IN-9

Description	ALK5-IN-9 (Compound 8h) is a potent and orally active inhibitor of TGFβRI (ALK5). ALK5-IN-9 inhibits ALK5 autophosphorylation and NIH3T3 cell activity with IC50 values of 25 nM and 74.6 nM, respectively. ALK5-IN-9 also shows favorable pharmacokinetic profile and ameliorated hERG inhibition. ALK5-IN-9 has the potential for the research of cancer disease[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Wang Z, et al. Synthesis and biological evaluation of 4-(pyridine-4-oxy)-3-(tetrahydro-2H-pyran-4-yl)-pyrazole derivatives as novel, potent of ALK5 receptor inhibitors. Bioorg Med Chem Lett. 2022;61:128552.

Molecular Formula	C₂₉H₃₅F₃N₆O₃
Molecular Weight	572.62

DC Chemicals Limited
China
Product Name: ALK5-IN-9
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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