ALK5-IN-9
Names
[ CAS No. ]:
2489611-06-3
[ Name ]:
ALK5-IN-9
Biological Activity
[Description]:
ALK5-IN-9 (Compound 8h) is a potent and orally active inhibitor of TGFβRI (ALK5). ALK5-IN-9 inhibits ALK5 autophosphorylation and NIH3T3 cell activity with IC50 values of 25 nM and 74.6 nM, respectively. ALK5-IN-9 also shows favorable pharmacokinetic profile and ameliorated hERG inhibition. ALK5-IN-9 has the potential for the research of cancer disease[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C29H35F3N6O3
[ Molecular Weight ]:
572.62