ALK5-IN-26

Names

[ CAS No. ]:
2785430-82-0

[ Name ]:
ALK5-IN-26

Biological Activity

[Description]:

ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 with an IC50 value ≤10 nM. ALK5-IN-26 can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

IC50: ≤10 nM (ALK5)[1]


[In Vitro]

ALK5-IN-26 (0-1 μM; 24 h) inhibits ALK5 with an IC50 value ≤10 nM, and shows selectivity of ALK2 IC50/ALK5 IC50 of a ratio ＜100[1].

[References]

[1]. Franz B, et al. ALK-5 INHIBITORS AND USES THEREOF. WO/2022/126133 A1. 2022.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H25FN8

[ Molecular Weight ]:
444.51

Related Compounds