Viral 2C protein inhibitor 1

Modify Date: 2024-04-11 19:29:16

Viral 2C protein inhibitor 1 Structure
Viral 2C protein inhibitor 1 structure
Common Name Viral 2C protein inhibitor 1
CAS Number 1594427-18-5 Molecular Weight 323.36
Density N/A Boiling Point N/A
Molecular Formula C19H18FN3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Viral 2C protein inhibitor 1


Viral 2C protein inhibitor 1 (compound 6aw) is a potent and broad-spectrum enterovirus antiviral agent, inhibiting viral 2C protein. Viral 2C protein inhibitor 1 inhibits multiple strains of EV-D68, EV-A71 and CVB3 with EC50s of 0.1~3.6 µM, and exhibits high selectivity index and relatively low cytotoxicity[1].

 Names

Name Viral 2C protein inhibitor 1

 Viral 2C protein inhibitor 1 Biological Activity

Description Viral 2C protein inhibitor 1 (compound 6aw) is a potent and broad-spectrum enterovirus antiviral agent, inhibiting viral 2C protein. Viral 2C protein inhibitor 1 inhibits multiple strains of EV-D68, EV-A71 and CVB3 with EC50s of 0.1~3.6 µM, and exhibits high selectivity index and relatively low cytotoxicity[1].
Related Catalog
Target

EC50: 0.1~0.2 µM (EV-D68), 3.1 µM (EV-A71), 0.2 µM (CVB3)[1]

References

[1]. Musharrafieh R, et al. Development of broad-spectrum enterovirus antivirals based on quinoline scaffold. Bioorg Chem. 2020 Aug;101:103981.

 Chemical & Physical Properties

Molecular Formula C19H18FN3O
Molecular Weight 323.36