Viral 2C protein inhibitor 1

Names

[ CAS No. ]:
1594427-18-5

[ Name ]:
Viral 2C protein inhibitor 1

Biological Activity

[Description]:

Viral 2C protein inhibitor 1 (compound 6aw) is a potent and broad-spectrum enterovirus antiviral agent, inhibiting viral 2C protein. Viral 2C protein inhibitor 1 inhibits multiple strains of EV-D68, EV-A71 and CVB3 with EC50s of 0.1~3.6 µM, and exhibits high selectivity index and relatively low cytotoxicity[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

EC50: 0.1~0.2 µM (EV-D68), 3.1 µM (EV-A71), 0.2 µM (CVB3)[1]


[References]

[1]. Musharrafieh R, et al. Development of broad-spectrum enterovirus antivirals based on quinoline scaffold. Bioorg Chem. 2020 Aug;101:103981.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H18FN3O

[ Molecular Weight ]:
323.36

Related Compounds