Acta poloniae pharmaceutica 2013-01-01

Identification and determination of selected histamine antagonists by densitometric method.

Krystyna Czerwińska, Elzbieta Wyszomirska, Aleksander P Mazurek

Index: Acta Pol. Pharm. 70(1) , 19-26, (2013)

Full Text: HTML

Abstract

The conditions for identification were determined for four histamine antagonists: clemastine fumarate, loratadine, cetirizine dihydrochloride and desloratadine by TLC (thin-layer chromatography) method. The selected chromatographic conditions were used to develop a densitometric method for the content determination of the histamine antagonists in medicinal products and substances. The statistical data showed adequate accuracy and precision of the developed methods.