Tetrahedron Letters

The reaction of vinyl Grignard reagents with 2-substituted nitroarenes: a new approach to the synthesis of 7-substituted indoles

G Bartoli, G Palmieri, M Bosco, R Dalpozzo

Index: Bartoli; Palmieri; Bosco; Dalpozzo Tetrahedron Letters, 1989 , vol. 30, # 16 p. 2129 - 2132

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Citation Number: 212

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The reaction of three moles of vinylmagnesium bromide with one mole of nitroarene leads to the formation of indoles after aqueous work up of the mixture. Good yields are obtained with ortho-substituted nitroarenes. ... (d) PG Gassman, Bergen TJ van, DP Gilbert, BW Cue Jr.