Structure–Activity Relationships (SAR) Research of Thiourea Derivatives as Dual Inhibitors Targeting both HIV??1 Capsid and Human Cyclophilin A

K Chen, Z Tan, M He, J Li, S Tang…

Index: Chemical Biology and Drug Design, , vol. 76, # 1 p. 25 - 33

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Citation Number: 10

Abstract

... Thiourea Derivatives as Dual Inhibitors Targeting both HIV-1 Capsid and Human Cyclophilin A. Chemical Biology & Drug ... followed the existing model and chose sulfamethoxazole, which showed good inhibitory activity in biological evaluation, as ... Chemical synthetic procedure. ...