ONE-POT SYNTHESIS OF ISOTHIOCYANATES FROM PRIMARY AMINES SYNTHESIS USING CYANAMIDE?

T Yamamoto, S Sugiyama, K Akimoto…

Index: Yamamoto, Tamotsu; Sugiyama, Susumu; Akimoto, Kenji; Hayashi, Kiyoshi Organic Preparations and Procedures International, 1992 , vol. 24, # 3 p. 346 - 349

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Citation Number: 8

Abstract

3 a) R= nC, H, b) R= n-C4H, c) sec-C, H, d) t-C4H, e) nC, H,, f) R= PhCH; CH, g) R=(C&O), Si (CH. J3 h) R=(C, H, O), Si (CHJ, i) R= C, H, j) R= 4-C $ C6H4 k) R= 4-C&OC6H, m) R= 4- ClC6H4 n-Propyl, n-butyl, sec-butyl, c-butyl, n-hexyl, 2-phenylethyl, 3-(trimethoxysilyl) propyl and 3-(triethoxysily1) propylamines were converted to dithiocarbamic acid with carbon disulfide and then to the corresponding isothiocyanates with CA in THF in high yields ...