2-Anisidine

Modify Date: 2025-08-21 20:33:42

2-Anisidine structure	Common Name	2-Anisidine
	CAS Number	90-04-0	Molecular Weight	123.152
	Density	1.1±0.1 g/cm3	Boiling Point	225.0±0.0 °C at 760 mmHg
	Molecular Formula	C₇H₉NO	Melting Point	3-6 °C(lit.)
	MSDS	Chinese USA	Flash Point	98.9±0.0 °C
	Symbol	GHS06, GHS08	Signal Word	Danger

Name	o-Anisidine
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	225.0±0.0 °C at 760 mmHg
Melting Point	3-6 °C(lit.)
Molecular Formula	C₇H₉NO
Molecular Weight	123.152
Flash Point	98.9±0.0 °C
Exact Mass	123.068413
PSA	35.25000
LogP	1.09
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.555
Stability	Stable. Incompatible with strong oxidizing agents, acid anhydrides, chloroformates, acids, some plastics, rubber. Air sensitive.
Water Solubility	13 g/L (20 ºC)

2-Anisidine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ5410000

CHEMICAL NAME :: o-Anisidine

CAS REGISTRY NUMBER :: 90-04-0

BEILSTEIN REFERENCE NO. :: 0386210

LAST UPDATED :: 199806

DATA ITEMS CITED :: 46

MOLECULAR FORMULA :: C7-H9-N-O

MOLECULAR WEIGHT :: 123.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1400 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes Blood - normocytic anemia Blood - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 870 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes Blood - normocytic anemia Blood - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 422 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: DNA damage

TYPE OF TEST :: DNA inhibition

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.5 mg/m3 (0.1 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,63,1982 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.1 ppm (0.5 mg/m3) (skin) DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,10,1973 OSHA PEL (Gen Indu):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.5 mg/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-AUSTRIA:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 0.5 mg/m3;STEL 1.5 mg/m3;Skin;Carcinogen JAN 1993 OEL-FRANCE:TWA 0.1 ppm (0.5 mg/m3);Skin;Carcinogen JAN 1993 OEL-GERMANY:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-INDIA:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-THE NETHERLANDS:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.5 mg/m3;Skin JAN 1993 OEL-RUSSIA:STEL 1 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.1 ppm (0.5 mg/m3);STEL 0.2 ppm;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 ppm (0.5 mg/m3);Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO o-ANISIDINE-air:10H CA TWA 0.5 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8302 No. of Facilities: 50 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 705 (estimated)

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H301-H311-H331-H341-H350
Precautionary Statements	P201-P261-P280-P301 + P310-P311
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;
Risk Phrases	R23/24/25;R45;R68
Safety Phrases	S53-S45
RIDADR	UN 2431 6.1/PG 3
WGK Germany	3
RTECS	BZ5410000
Packaging Group	III
Hazard Class	6.1
HS Code	2922199090

Precursor 10
CAS#:91-23-6 nitroanisole CAS#:578-57-4 bromoanisole CAS#:529-28-2 iodoanisole CAS#:766-51-8 2-Chloroanisole
CAS#:23896-88-0 Formamide,N-(2-... CAS#:20442-97-1 2-Methoxyphenyl... CAS#:613-55-8 bis(2-methoxyph... CAS#:64-18-6 Formic Acid
CAS#:110-71-4 1,2-dimethoxyethane CAS#:74-87-3 Chloromethane
DownStream 10
CAS#:110788-32-4 (2-methoxypheny... CAS#:106700-04-3 2-chloro-N-(2-m... CAS#:104007-09-2 DIETHYL 2-(((2-... CAS#:105529-94-0 8-methoxy-9H-py...
CAS#:10530-51-5 2-methoxyanilin... CAS#:103248-23-3 2-methoxy-N-[(6... CAS#:39538-68-6 2-Methoxy-4-met... CAS#:3189-22-8 7-Methoxyindole
CAS#:461699-81-0 2-METHOXY-4-(4,... CAS#:52749-50-5 8-HYDROXY-3,4-D...

HS Code	2922291000
Summary	2922291000 4-methoxyaniline。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:6.5%。General tariff:30.0%

Toxicological assessment of kretek cigarettes: Part 1: background, assessment approach, and summary of findings.

Regul Toxicol Pharmacol 70 Suppl 1 , S2-14, (2014)

This publication introduces a series of six other publications describing the toxicological assessment of kretek cigarettes, i.e., cigarettes characterized primarily by the use of a significant amount...

Monoarylamines in the general population--a cross-sectional population-based study including 1004 Bavarian subjects.

Int. J. Hyg. Environ. Health 212(3) , 298-309, (2009)

The population-based cross-sectional study including 1004 Bavarian volunteers aged 3 up to 84 years (median: 42 years) was aimed to quantify the internal burden of monocyclic arylamines in the general...

Redox cycling in the metabolism of the environmental pollutant and suspected human carcinogen o-anisidine by rat and rabbit hepatic microsomes.

Chem. Res. Toxicol. 21(8) , 1610-21, (2008)

We investigated the ability of hepatic microsomes from rat and rabbit to metabolize 2-methoxyaniline (o-anisidine), an industrial and environmental pollutant and a bladder carcinogen for rodents. Usin...

Benzenamine, 2-methoxy-

2-Aminoanisole

o-Methoxyphenylamine

2-Anisidine

2-Methoxyaniline

1-amino-2-methoxy-benzene

o-Anisidine

ORTHO ANISIDINE

ortho-Methoxyphenylamine

2-methoxy-phenylamine

ortho-Methoxyaniline

EINECS 201-963-1

ortho-Aminoanisole

MFCD00007688

2-methoxyphenylamine

o-Aminoanisole

2-Methoxybenzenamine

ortho-Anisidine

o-Amnoanisde

2-Anisidin

O-ANISOLE

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-Anisidine
Price: Check
Purity: 99.5%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 2-Anisidine
Price: ￥95.0/100ml ￥265.0/500ml
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: o-Anisidine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: o-Anisidine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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2-Anisidine

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

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Synonyms

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