Grignard Reductions. IX. 1, 2, 3 Further Studies on the Reduction of Acid Halides

FC Whitmore, JS Whitaker, WA Mosher…

Index: Whitmore et al. Journal of the American Chemical Society, 1941 , vol. 63, p. 647

Full Text: HTML

Citation Number: 22

Abstract

Summary Experimental proof is presented of (1) an increased yield of carboxylic acids by employing step-wise chromic acid oxidation of S-alkylquinolines and (2) an increase in the velocity of reaction, where chromic acid anhydride is employed, by the addition of potassium acid sulfate. The direct conversion of Bz-ethylquinolines to corresponding Bz-quinolyl methyl ketones through oxidation with chromic acid anhydride or dichromate is reported.