AS-136A

AS-136A Structure
AS-136A structure
Common Name AS-136A
CAS Number 949898-66-2 Molecular Weight 416.41800
Density N/A Boiling Point N/A
Molecular Formula C17H19F3N4O3S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: synthesis, structure-activity relationships, and pharmacokinetics.

J. Med. Chem. 55(9) , 4220-30, (2012)

The measles virus (MeV), a member of the paramyxovirus family, is an important cause of pediatric morbidity and mortality worldwide. In an effort to provide therapeutic treatments for improved measles management, we previously identified a small, non-nucleosi...

Target analysis of the experimental measles therapeutic AS-136A.

Antimicrob. Agents Chemother. , (2009)

No effective therapeutic is currently in place for improved case management of severe measles or the rapid control of outbreaks. Through high-throughput screening, we recently identified a novel small-molecule class that potently blocks activity of the measle...