Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate
Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate structure
|
Common Name | Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate | ||
|---|---|---|---|---|
| CAS Number | 5909-24-0 | Molecular Weight | 232.687 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 335.7±22.0 °C at 760 mmHg | |
| Molecular Formula | C8H9ClN2O2S | Melting Point | 60-63 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 156.8±22.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors.
Bioorg. Med. Chem. Lett. 18(7) , 2355-61, (2008) A series of pyrimidinopyridones has been designed, synthesized and shown to be potent and selective inhibitors of the FMS tyrosine kinase. Introduction of an amide substituent at the 6-position of the pyridone core resulted in a significant potency increase. ... |
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