Tris(2-pyridylmethyl)amine
Tris(2-pyridylmethyl)amine structure
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Common Name | Tris(2-pyridylmethyl)amine | ||
|---|---|---|---|---|
| CAS Number | 16858-01-8 | Molecular Weight | 290.362 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 409.8±40.0 °C at 760 mmHg | |
| Molecular Formula | C18H18N4 | Melting Point | 85-89ºC | |
| MSDS | Chinese USA | Flash Point | 201.6±27.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is required for production of progeny viruses.
J. Virol. 89(9) , 4918-31, (2015) The ORF45 protein of Kaposi's sarcoma-associated herpesvirus (KSHV) is a gammaherpesvirus-specific immediate-early tegument protein. Our previous studies have revealed its crucial roles in both early and late stages of KSHV infection. In this study, we survey... |
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Inhibition of basal JNK activity by small interfering RNAs enhances cisplatin sensitivity and decreases DNA repair in T98G glioblastoma cells.
Oncol. Rep. 33(1) , 413-8, (2014) Inhibition of basal Jun kinase (JNK) activity by small interfering RNAs (siRNAs) enhances cisplatin sensitivity and decreases DNA repair in T98G glioblastoma cells. Although the JNK pathway has been extensively studied in recent years, little is known concern... |
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Triterpene glycosides and other polar constituents of shea (Vitellaria paradoxa) kernels and their bioactivities.
Phytochemistry 108 , 157-70, (2014) The MeOH extract of defatted shea (Vitellaria paradoxa; Sapotaceae) kernels was investigated for its constituents, and fifteen oleanane-type triterpene acids and glycosides, two steroid glucosides, two pentane-2,4-diol glucosides, seven phenolic compounds, an... |
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Cellular Anti-Melanogenic Effects of a Euryale ferox Seed Extract Ethyl Acetate Fraction via the Lysosomal Degradation Machinery.
Int. J. Mol. Sci. 16 , 9217-35, (2015) The aim of this study was to investigate the effect of ethyl acetate fraction of Euryale ferox seed extracts (Efse-EA) on melanogenesis in immortalized mouse melanocyte cell line, melan-a. Efse-EA showed strong dose-dependent mushroom tyrosinase inhibitory ac... |
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Antioxidant and Anti-inflammatory Activities of Essential Oil and Extracts of Piper miniatum.
Nat. Prod. Commun. 10 , 2005-8, (2016) The chemical composition of the essential oil and antioxidant and anti-inflammatory activities of the extracts from Piper miniatum were determined. GC and GC-MS analysis of the essential oil resulted in the identification of 64 components, accounting for 89.2... |
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Curcumin relieves TPA-induced Th1 inflammation in K14-VEGF transgenic mice.
Int. Immunopharmacol. 25(2) , 235-41, (2015) Curcumin has been confirmed to have anti-inflammatory properties in addition to the ability to decrease the expression of pro-inflammatory cytokines in keratinocytes. It was suggested that the interleukin-23 (IL-23)/IL-17A cytokine axis played a critical role... |
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Modular Design of Self-Assembling Peptide-Based Nanotubes.
J. Am. Chem. Soc. 137 , 10554-62, (2015) An ability to design peptide-based nanotubes (PNTs) rationally with defined and mutable internal channels would advance understanding of peptide self-assembly, and present new biomaterials for nanotechnology and medicine. PNTs have been made from Fmoc dipepti... |
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A Novel Electrochemiluminescence Immunosensor for the Analysis of HIV-1 p24 Antigen Based on P-RGO@Au@Ru-SiO₂ Composite.
ACS Appl. Mater. Interfaces 7 , 24438-45, (2015) Ru(bpy)3(2+)-doped silica (Ru-SiO2) nanoparticles and gold-nanoparticle-decorated graphene (P-RGO@Au) were combined to form a P-RGO@Au@Ru-SiO2 composite. The composite was used to develop a novel sandwich-type electrochemiluminescence immunosensor for the ana... |
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Apoptin interacts with and regulates the activity of protein kinase C beta in cancer cells.
Apoptosis 20(6) , 831-42, (2015) Apoptin, the VP3 protein from chicken anaemia virus (CAV), induces tumour cell-specific cell death and represents a potential future anti-cancer therapeutic. In tumour but not in normal cells, Apoptin is phosphorylated and translocates to the nucleus, enablin... |
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Viral Bcl-2 Encoded by the Kaposi's Sarcoma-Associated Herpesvirus Is Vital for Virus Reactivation.
J. Virol. 89(10) , 5298-307, (2015) The Kaposi's sarcoma-associated herpesvirus (KSHV) open reading frame 16 (orf16) encodes a viral Bcl-2 (vBcl-2) protein which shares sequence and functional homology with the Bcl-2 family. Like its cellular homologs, vBcl-2 protects various cell types from ap... |