Rhododendrol
Rhododendrol structure
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Common Name | Rhododendrol | ||
|---|---|---|---|---|
| CAS Number | 501-96-2 | Molecular Weight | 166.22 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 315.4±17.0 °C at 760 mmHg | |
| Molecular Formula | C10H14O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 153.4±15.5 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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T-Cell Responses to Tyrosinase-Derived Self-Peptides in Patients with Leukoderma Induced by Rhododendrol: Implications for Immunotherapy Targeting Melanoma.
Dermatology 232 , 44-9, (2016) Rhododendrol, a phenolic compound contained in lightening/whitening cosmetics, can bind and inhibit tyrosinase and was reported to induce leukoderma in Japan. Only 2% of the cosmetics users are affected, and tacrolimus is effective in treatment of the conditi... |
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Rhododendrol, a depigmentation-inducing phenolic compound, exerts melanocyte cytotoxicity via a tyrosinase-dependent mechanism.
Pigment Cell Melanoma Res. 27(5) , 754-63, (2014) Rhododendrol, an inhibitor of melanin synthesis developed for lightening/whitening cosmetics, was recently reported to induce a depigmentary disorder principally at the sites of repeated chemical contact. Rhododendrol competitively inhibited mushroom tyrosina... |
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