Oil Red O

Oil Red O Structure
Oil Red O structure
Common Name Oil Red O
CAS Number 1320-06-5 Molecular Weight 408.495
Density 1.2±0.1 g/cm3 Boiling Point 638.8±55.0 °C at 760 mmHg
Molecular Formula C26H24N4O Melting Point 120ºC
MSDS Chinese USA Flash Point 439.7±20.8 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging.

Proc. Natl. Acad. Sci. U. S. A. 111(37) , E3880-9, (2014)

Many metabolic pathways are critically regulated during development and aging but little is known about the molecular mechanisms underlying this regulation. One key metabolic cascade in eukaryotes is the mevalonate pathway. It catalyzes the synthesis of stero...

Autophagy facilitates secretion and protects against degeneration of the Harderian gland.

Autophagy 11(2) , 298-313, (2015)

The epithelial derived Harderian gland consists of 2 types of secretory cells. The more numerous type A cells are responsible for the secretion of lipid droplets, while type B cells produce dark granules of multilamellar bodies. The process of autophagy is co...

The role of lipid droplets and adipocytes in cancer. Raman imaging of cell cultures: MCF10A, MCF7, and MDA-MB-231 compared to adipocytes in cancerous human breast tissue.

Analyst 140(7) , 2224-35, (2015)

We have studied live non-malignant (MCF10A), mildly malignant (MCF7) and malignant (MDA-MB-231) breast cancer cells and human breast cancer tissue. We demonstrate the first application of Raman imaging and spectroscopy in diagnosing the role of lipid droplets...

Relative percentage and zonal distribution of mesenchymal progenitor cells in human osteoarthritic and normal cartilage.

Arthritis. Res. Ther. 13(2) , R64, (2011)

Mesenchymal stem cells (MSC) are highly attractive for use in cartilage regeneration. To date, MSC are usually recruited from subchondral bone marrow using microfracture. Recent data suggest that isolated cells from adult human articular cartilage, which expr...

Adipogenic differentiation of adipose-derived stem cells in 3-dimensional spheroid cultures (microtissue): implications for the reconstructive surgeon.

J. Plast. Reconstr. Aesthet. Surg. 67(12) , 1726-34, (2014)

Adipose-derived stem cells (ADSC) can be readily extracted from adipose tissue, expanded in vitro, and have the capacity to differentiate into multiple cell lineages. This makes this cell type of great interest to the field of regenerative medicine. This stud...

Lentiviral-mediated genetic correction of hematopoietic and mesenchymal progenitor cells from Fanconi anemia patients.

Mol. Ther. 17(6) , 1083-92, (2009)

Previous clinical trials based on the genetic correction of purified CD34(+) cells with gamma-retroviral vectors have demonstrated clinical efficacy in different monogenic diseases, including X-linked severe combined immunodeficiency, adenosine deaminase defi...

Fructose impairs glucose-induced hepatic triglyceride synthesis.

Lipids Health Dis. 10 , 20, (2011)

Obesity, type 2 diabetes and hyperlipidemia frequently coexist and are associated with significantly increased morbidity and mortality. Consumption of refined carbohydrate and particularly fructose has increased significantly in recent years and has paralled ...

Analysis and testing of biological stains--the Biological Stain Commission Procedures.

Biotech. Histochem. 77(5&6) , 237-275, (2002)

Intestinal alkaline phosphatase prevents metabolic syndrome in mice.

Proc. Natl. Acad. Sci. U. S. A. 110(17) , 7003-8, (2013)

Metabolic syndrome comprises a cluster of related disorders that includes obesity, glucose intolerance, insulin resistance, dyslipidemia, and fatty liver. Recently, gut-derived chronic endotoxemia has been identified as a primary mediator for triggering the l...

Therapeutic potential of human adipose-derived stem cells (ADSCs) from cancer patients: a pilot study.

PLoS ONE 9(11) , e113288, (2014)

Mesenchymal stem cells from adipose tissue (ADSCs) are an important source of cells for regenerative medicine. The therapeutic effect of culture-expanded adipose derived stem cells has been shown; however, optimal xeno-free culture conditions remain to be det...