Perfluoroacetyl(2-furoyl)methane
Perfluoroacetyl(2-furoyl)methane structure
|
Common Name | Perfluoroacetyl(2-furoyl)methane | ||
|---|---|---|---|---|
| CAS Number | 326-90-9 | Molecular Weight | 206.119 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 229.7±35.0 °C at 760 mmHg | |
| Molecular Formula | C8H5F3O3 | Melting Point | 19-21ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 92.7±25.9 °C | |
|
4,7-Dichloro benzothien-2-yl sulfonylaminomethyl boronic acid: first boronic acid-derived beta-lactamase inhibitor with class A, C, and D activity.
Bioorg. Med. Chem. Lett. 20 , 2622-4, (2010) 4,7-Dichloro-1-benzothien-2-yl sulfonylaminomethyl boronic acid (DSABA, Compound I) was discovered as the first boronic acid-based class D beta-lactamase inhibitor. It exhibited an IC(50) of 5.6 microM against OXA-40. The compound also inhibited class A and C... |
|
|
Topography of the cristae membrane as elucidated by a new inhibitor, trifluorofurylbutanedione.
Biochem. Biophys. Res. Commun. 55(1) , 169-73, (1973)
|
|
|
Antiplasmodial structure-activity relationship of 3-trifluoromethyl-2-arylcarbonylquinoxaline 1,4-di-N-oxide derivatives.
Exp. Parasitol. 118(1) , 25-31, (2008) Derivatives of 3-trifluoromethyl-2-arylcarbonylquinoxaline 1,4-di-N-oxide (4b-g, 5b-g, 6a-g) were synthesized and evaluated for their capacity to inhibit the growth of chloroquine-resistant Plasmodium falciparum FCB1 strain in culture. Compound 7-chloro-2-(2-... |
|
|
Induction of apoptosis by beta-diketones in human tumor cells.
Anticancer Res. 24(2B) , 711-7, (2004) A variety of beta-diketones were evaluated for their cytotoxic profiles against oral human normal and tumor cells. Among 22 compounds (BD1-22) tested, the cytotoxicity of 3-formylchromone (BD17) (CC50=7.8 microg/mL) against human oral squamous cell carcinoma ... |
|
|
Formation of unusual glutamate conjugates of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC 423) and its analogs: the role of gamma-glutamyltranspeptidase in the biotransformation of benzylamines.
Drug Metab. Dispos. 29(10) , 1296-306, (2001) The role of gamma-glutamyltranspeptidase (GGT) in transferring glutamate from endogenous glutathione (GSH) to the benzylamine moiety of a compound, such as 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-... |
|
|
An efficient entry to perfluoroalkyl substituted azoles starting from β-perfluoroalkyl-β-dicarbonyl compounds. Bravo P, et al.
Tetrahedron 50(29) , 8827-8836 , (1994)
|
|
|
Acyclic tertiary diamines and 1, 4, 7,10-tetraazacyclododecane with fluorine-containing β-diketones: Leading to low melting ionic adducts. Gupta OD, et al.
J. Fluor. Chem. 126(8) , 1222-1229, (2005)
|
|
|
X-ray structure and temperature dependent luminescent properties of two bimetallic europium complexes. Swavey S, et al.
Polyhedron 27(3) , 1061-1069, (2008)
|
|
|
Conformation, structure, intramolecular hydrogen bonding, and vibrational assignment of 4,4, 4-trifluoro-1-(2-furyl)-1,3-butanedione. Tayyari SF, et al.
J. Mol. Struct. 8882(1) , 153-167, (2008)
|
|
|
Synthesis and biological evaluation of new 2-arylcarbonyl-3-trifluoromethylquinoxaline 1,4-di-N-oxide derivatives and their reduced analogues. Solano B, et al.
J. Med. Chem. 50(22) , 5485-5492, (2007)
|