Cefmetazole Sodium

Cefmetazole Sodium Structure
Cefmetazole Sodium structure
Common Name Cefmetazole Sodium
CAS Number 56796-39-5 Molecular Weight 493.516
Density 1.75 g/cm3 Boiling Point N/A
Molecular Formula C15H16N7NaO5S3 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

Chimeric mice with humanized liver.

Toxicology 246(1) , 9-17, (2008)

Recently, chimeric mice with humanized liver were established by transplanting human hepatocytes into an urokinase-type plasminogen activator(+/+)/severe combined immunodeficient transgenic mouse line. The replacement with human hepatocytes is more than 80-90...

Usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery

Asian J. Surg. 35(2) , 81-7, (2012)

Objective We retrospectively evaluated the usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery.

Involvement of multidrug resistance-associated protein 4 in efflux transport of prostaglandin E(2) across mouse blood-brain barrier and its inhibition by intravenous administration of cephalosporins.

J. Pharmacol. Exp. Ther. 333 , 912-919, (2010)

Prostaglandin E(2) (PGE(2)) acts as a modulator of synaptic signaling and excitability in the brain. Because PGE(2) is barely inactivated enzymatically in adult brain, its brain level is considered to be controlled by efflux transport across the blood-brain b...

Verification of cefmetazole and cefpodoxime proxetil contamination to other pharmaceuticals by liquid chromatography-tandem mass spectrometry.

Chem. Pharm. Bull. 54(10) , 1469-72, (2006)

Cross-contamination is a critical issue for pharmaceutical manufacturing, especially for beta-lactam antibiotics. Thus, an analytical method for the simultaneous determination of beta-lactam antibiotics cefmetazole (CMZ) and cefpodoxime proxetil (CPDXPR) cont...

Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.

J. Bone Joint Surg. Am. 95(4) , 291-6, (2013)

Appropriate pain management affects outcome after hip fracture surgery. Although multimodal pain management is commonly used for pain control for patients undergoing elective surgery, few studies have evaluated its use in those undergoing hip fracture surgery...

Humanization of excretory pathway in chimeric mice with humanized liver.

Toxicol. Sci. 97(2) , 533-8, (2007)

The liver of a chimeric urokinase-type plasminogen activator (uPA)(+/+)/severe combined immunodeficient (SCID) mouse line recently established in Japan could be replaced by more than 80% with human hepatocytes. We previously reported that the chimeric mice wi...

Multicenter prospective randomized phase II study of antimicrobial prophylaxis in low-risk patients undergoing colon surgery.

Surg. Today 40(10) , 954-7, (2010)

Postoperative antimicrobial therapy is generally administered as standard prophylaxis against postoperative infection, despite a lack of sufficient evidence for its usefulness. This study was a phase II study to evaluate the necessity of postoperative antibio...

Change of drug excretory pathway by CCl4-induced liver dysfunction in rat.

Biochem. Pharmacol. 74(3) , 488-95, (2007)

Liver dysfunction affects the pharmacokinetics of drugs. The liver plays an important role in drug excretion as well as drug metabolism and pharmacokinetics. In the present study, the relationship between changes in the cefmetazole (CMZ) excretory pathway and...

Clinical impact of preoperative cholangitis after biliary drainage in patients who undergo pancreaticoduodenectomy on postoperative pancreatic fistula.

Am. Surg. 80(1) , 36-42, (2014)

The objective of this study was to examine whether the development of cholangitis after preoperative biliary drainage (PBD) can increase the incidence of postoperative pancreatic fistula (POPF). The study population included 185 consecutive patients who under...

Determination of cefmetazole residue at pharmaceutical manufacturing facilities by chemiluminescence flow injection analysis.

J. Pharm. Biomed. Anal. 41(2) , 599-602, (2006)

Application of a sensitive and rapid flow injection analysis (FIA) method with luminol chemiluminescence detection for determination of trace amounts of cefmetazole (CMZ) in cephamycin antibiotic residue in pharmaceutical manufacturing facilities and on pharm...