Aniline
Aniline structure
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Common Name | Aniline | ||
|---|---|---|---|---|
| CAS Number | 62-53-3 | Molecular Weight | 93.127 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 184.4±0.0 °C at 760 mmHg | |
| Molecular Formula | C6H7N | Melting Point | -6.2 °C | |
| MSDS | Chinese USA | Flash Point | 70.0±0.0 °C | |
| Symbol |
GHS05, GHS06, GHS08, GHS09 |
Signal Word | Danger | |
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Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
J. Clin. Invest. 125(2) , 607-20, (2015) Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited nephropathy responsible for 4%-10% of end-stage renal disease cases. Mutations in the genes encoding polycystin-1 (PC1, PKD1) or polycystin-2 (PC2, PKD2) cause ADPKD, and PKD1 mutation... |
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cIEF for rapid pKa determination of small molecules: a proof of concept.
Eur. J. Pharm. Sci. 63 , 14-21, (2014) A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) were compared: (i) a hydroxypropylcellulose (HPC) coated cap... |
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In vitro characterization of self-assembled anterior cruciate ligament cell spheroids for ligament tissue engineering.
Histochem. Cell Biol. 143(3) , 289-300, (2015) Tissue engineering of an anterior cruciate ligament (ACL) implant with functional enthesis requires site-directed seeding of different cell types on the same scaffold. Therefore, we studied the suitability of self-assembled three-dimensional spheroids generat... |
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Ameliorative effect of mepenzolate bromide against pulmonary fibrosis.
J. Pharmacol. Exp. Ther. 350(1) , 79-88, (2014) Idiopathic pulmonary fibrosis is thought to involve lung injury caused by reactive oxygen species (ROS), which in turn is followed by abnormal fibrosis. A transforming growth factor (TGF)-β1-induced increase in myofibroblast number plays an important role in ... |
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Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins
Bioorg. Med. Chem. 17 , 896-904, (2009) This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoretical molecular descriptors, calculated solely from the mole... |
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QSAR study and synthesis of new phenyltropanes as ligands of the dopamine transporter (DAT).
Bioorg. Med. Chem. 20 , 1388-95, (2012) The dopamine transporter (DAT) plays a pivotal role in the regulation of dopamine neurotransmission, and is involved in a number of physiological functions and brain disorders. Furthermore the DAT analysis by molecular imaging techniques is a useful tool for ... |
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Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
J. Med. Chem. 48 , 3269-79, (2005) Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in the... |
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Aniline-modified porous graphitic carbon for hydrophilic interaction and attenuated reverse phase liquid chromatography.
J. Chromatogr. A. 1373 , 17-24, (2014) Most stationary phases for hydrophilic interaction liquid chromatography (HILIC) and reversed phase liquid chromatography (RPLC) are based on silica. Porous graphitic carbon (PGC) is an attractive alternative to silica-based phases due to its chemical and the... |
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Integrated metabolomic and proteomic analysis reveals systemic responses of Rubrivivax benzoatilyticus JA2 to aniline stress.
J. Proteome Res. 14(2) , 711-27, (2015) Aromatic amines are widely distributed in the environment and are major environmental pollutants. Although degradation of aromatic amines is well studied in bacteria, physiological adaptations and stress response to these toxic compounds is not yet fully unde... |
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Dispersive micro-solid-phase extraction of benzodiazepines from biological fluids based on polyaniline/magnetic nanoparticles composite.
Anal. Chim. Acta 844 , 80-9, (2014) In this study, diverse types of Fe3O4 nanocomposites modified by polyaniline, polypyrrole, and aniline-pyrrole copolymer were synthesized through chemical oxidative polymerization process for dispersive-μ-solid phase extraction (D-μ-SPE) in the presence of va... |