Chloro(2, 2′: 6′, 2″-terpyridine)platinum(II) chloride dihydrate

Chloro(2, 2′: 6′, 2″-terpyridine)platinum(II) chloride dihydrate Structure
Chloro(2, 2′: 6′, 2″-terpyridine)platinum(II) chloride dihydrate structure
Common Name Chloro(2, 2′: 6′, 2″-terpyridine)platinum(II) chloride dihydrate
CAS Number 151120-25-1 Molecular Weight 535.28200
Density N/A Boiling Point N/A
Molecular Formula C15H15Cl2N3O2Pt Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Metallointercalation reagents. 2-hydroxyethanethiolato(2,2',2'-terpyridine)-platinum(II) monocation binds strongly to DNA by intercalation.

Proc. Natl. Acad. Sci. U. S. A. 71 , 3839, (1974)

The red, cationic complex 2-hydroxy-ethanethiolato(2,2',2''-terpyridine)platinum(II), [(terpy)-Pt(SCH(2)CH(2)OH)](+), binds strongly to DNA by a mechanism involving intercalation. By means of fluorescence spectroscopy, the platinum complex was shown to inhibi...

S. J. Lippard

Acc. Chem. Res. 11 , 211, (1987)

E.M.A. Ratilla et al.

J. Am. Chem. Soc. 109 , 4592, (1987)