AG 18
AG 18 structure
|
Common Name | AG 18 | ||
|---|---|---|---|---|
| CAS Number | 118409-57-7 | Molecular Weight | 186.167 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 421.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C10H6N2O2 | Melting Point | 225ºC | |
| MSDS | USA | Flash Point | 208.5±28.7 °C | |
|
Regulation of store-operated Ca2+ entry in pulmonary artery smooth muscle cells.
Cell Calcium 46(2) , 99-106, (2009) Store-operated Ca2+ entry (SOCE) is an important mechanism for Ca2+ influx in smooth muscle cells; however the activation and regulation of this influx pathway are incompletely understood. In the present study we have examined the effect of several protein ki... |
|
|
Spatio-temporal cellular dynamics of the Arabidopsis flagellin receptor reveal activation status-dependent endosomal sorting.
Plant Cell 24(10) , 4205-19, (2012) The activity of surface receptors is location specific, dependent upon the dynamic membrane trafficking network and receptor-mediated endocytosis (RME). Therefore, the spatio-temporal dynamics of RME are critical to receptor function. The plasma membrane rece... |
|
|
Swelling-activated K+ efflux and regulatory volume decrease efficiency in human bronchial epithelial cells.
J. Membr. Biol. 214(1) , 33-41, (2006) This study describes the correlation between cell swelling-induced K+ efflux and volume regulation efficiency evaluated with agents known to modulate ion channel activity and/or intracellular signaling processes in a human bronchial epithelial cell line, 16HB... |
|
|
Rapid regulation of dopamine transporters by tyrosine kinases in rat neuronal preparations.
J. Neurochem. 101(5) , 1258-71, (2007) Termination of dopamine neurotransmission is primarily controlled by the plasma membrane-localized dopamine transporter. In this study, we investigated how this transporter is regulated by tyrosine kinases in neuronal preparations. In rat dorsal striatal syna... |
|
|
Role of kinases and G-proteins in the hyposmotic stimulation of cardiac IKs.
Biochim. Biophys. Acta 1758(10) , 1641-52, (2006) Exposure of cardiac myocytes to hyposmotic solution stimulates slowly-activating delayed-rectifying K(+) current (I(Ks)) via unknown mechanisms. In the present study, I(Ks) was measured in guinea-pig ventricular myocytes that were pretreated with modulators o... |
|
|
Involvement of tyrosine kinase in the hyposmotic stimulation of I Ks in guinea-pig ventricular myocytes.
Pflugers Arch. 456(3) , 489-500, (2008) The objective of this study was to investigate the involvement of tyrosine phosphorylation in the hyposmotic stimulation of cardiac I Ks, a slowly activating delayed-rectifier K+ current that promotes repolarization of the action potential. The current was re... |
|
|
Molecular basis for genistein-induced inhibition of Kir2.3 currents.
Pflugers Arch. 456(2) , 413-23, (2008) Inwardly rectifying potassium channels play an important role in the maintenance of membrane potential in neurons and myocardium. Identification of functional regulation mechanisms concerning these channels may lead to the development of specific modulators f... |
|
|
Differential effects of intravenous anesthetics on capacitative calcium entry in human pulmonary artery smooth muscle cells.
Am. J. Physiol. Lung Cell. Mol. Physiol. 294(5) , L1007-12, (2008) We assessed the roles of the protein kinase C (PKC) and the tyrosine kinase (TK) signaling pathways in regulating capacitative calcium entry (CCE) in human pulmonary artery smooth muscle cells (PASMCs) and investigated the effects of intravenous anesthetics (... |
|
|
Effects of tyrosine kinase and phosphatase inhibitors on microtubules in Arabidopsis root cells.
Cell Biol. Int. 32(6) , 630-7, (2008) To investigate the role of tyrosine phosphorylation/dephosphorylation processes in plant cells the morphology of Arabidopsis thaliana primary roots and the organization of cortical microtubules (MTs) were studied after inhibition of protein tyrosine kinases (... |
|
|
Regulation of K-Cl cotransport in erythrocytes of frog Rana temporaria by commonly used protein kinase and protein phosphatase inhibitors.
J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. 180(3) , 385-91, (2010) Recently (Agalakova and Gusev in J Comp Physiol 179:443-450, 2009), we demonstrated that the activity of K-Cl cotransport (KCC) in frog red blood cells is inhibited under stimulation of protein kinase C (PKC) with phorbol ester PMA (12-myristate-13-acetate). ... |