1,2-Dilinoleoyl-3-Palmitoyl-rac-glycerol

1,2-Dilinoleoyl-3-Palmitoyl-rac-glycerol Structure
1,2-Dilinoleoyl-3-Palmitoyl-rac-glycerol structure
Common Name 1,2-Dilinoleoyl-3-Palmitoyl-rac-glycerol
CAS Number 2190-15-0 Molecular Weight 855.36300
Density 0.928g/cm3 Boiling Point 800.7ºC at 760 mmHg
Molecular Formula C55H98O6 Melting Point -4--3°C (lit.)
MSDS USA Flash Point 298.6ºC

The coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lck.

Proc. Natl. Acad. Sci. U. S. A. 112(13) , E1604-13, (2015)

CD4 molecules on the surface of T lymphocytes greatly augment the sensitivity and activation process of these cells, but how it functions is not fully understood. Here we studied the spatial organization of CD4, and its relationship to T-cell antigen receptor...

Frataxin knockdown in human astrocytes triggers cell death and the release of factors that cause neuronal toxicity.

Neurobiol. Dis. 76 , 1-12, (2015)

Friedreich's ataxia (FA) is a recessive, predominantly neurodegenerative disorder caused in most cases by mutations in the first intron of the frataxin (FXN) gene. This mutation drives the expansion of a homozygous GAA repeat that results in decreased levels ...

Fine-Tuning the Surface of Forward Osmosis Membranes via Grafting Graphene Oxide: Performance Patterns and Biofouling Propensity.

ACS Appl. Mater. Interfaces 7 , 18004-16, (2015)

Graphene oxide (GO) nanosheets were attached to the polyamide selective layer of thin film composite (TFC) forward osmosis (FO) membranes through a poly L-Lysine (PLL) intermediary using either layer-by-layer or hybrid (H) grafting strategies. Fourier transfo...

Sprayed cells and polyelectrolyte films for biomaterial functionalization: the influence of physical PLL-PGA film treatments on dental pulp cell behavior.

Macromol. Biosci. 14(12) , 1771-82, (2014)

Further development of biomaterials is expected as advanced therapeutic products must be compliant to good manufacturing practice regulations. A spraying method for building-up polyelectrolyte films followed by the deposition of dental pulp cells by spraying ...

Thymidine kinase gene delivery using curcumin loaded peptide micelles as a combination therapy for glioblastoma.

Pharm. Res. 32(2) , 528-37, (2015)

The effect of the combination therapy of curcumin and the herpes simplex virus thymidine kinase (HSVtk) gene using R7L10 as a carrier was evaluated in a glioblastoma animal model.Curcumin was loaded into the cores of R7L10 peptide micelles using an oil-in-wat...

Influence of supporting polyelectrolyte layers on the coverage and stability of silver nanoparticle coatings.

J. Colloid. Interface Sci. 445 , 205-12, (2015)

Deposition mechanisms of citrate-stabilized silver nanoparticles 15 nm in diameter on cationic polyelectrolyte supporting layers were evaluated. Initially, the bulk and the electrokinetic properties of cationic polyelectrolytes and their monolayers on mica we...

RGD-peptide modified alginate by a chemoenzymatic strategy for tissue engineering applications.

J. Biomed. Mater. Res. A 103(3) , 896-906, (2015)

One of the main challenges in tissue engineering and regenerative medicine is the ability to maintain optimal cell function and survival post-transplantation. Biomaterials such as alginates are commonly used for immunoisolation, while they may also provide st...

In vivo monitoring of rat macrophages labeled with poly(l-lysine)-iron oxide nanoparticles.

J. Biomed. Mater. Res. B. Appl. Biomater. 103 , 1141-8, (2015)

Coprecipitation of FeCl2 and FeCl3 with aqueous ammonia was used to prepare iron oxide nanoparticles dispersible in aqueous medium. Oxidation of the particles with sodium hypochlorite then yielded maghemite (γ-Fe2 O3 ) nanoparticles which were coated with two...

3D brown adipogenesis to create "Brown-Fat-in-Microstrands".

Biomaterials 75 , 123-34, (2015)

The ability of brown adipocytes (fat cells) to dissipate energy as heat shows great promise for the treatment of obesity and other metabolic disorders. Employing pluripotent stem cells, with an emphasis on directed differentiation, may overcome many issues cu...

Liposomal drug deposits in poly(dopamine) coatings: effect of their composition, cell type, uptake pathway considerations, and shear stress.

Macromol. Biosci. 14(12) , 1677-87, (2014)

Implantable devices equipped with coatings which have the ability to carry and deliver active compounds are of great interest. We report the assembly of liposome-containing poly(dopamine) films, and their interaction with adhering cells. The liposome composit...