5-Chloro-1,3-thiazol-2-amine hydrochloride (1:1)

5-Chloro-1,3-thiazol-2-amine hydrochloride (1:1) Structure
5-Chloro-1,3-thiazol-2-amine hydrochloride (1:1) structure
Common Name 5-Chloro-1,3-thiazol-2-amine hydrochloride (1:1)
CAS Number 55506-37-1 Molecular Weight 171.048
Density N/A Boiling Point 260.5ºC at 760 mmHg
Molecular Formula C3H4Cl2N2S Melting Point 164-167 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 111.3ºC
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Effects of new ubiquinone-imidazo[2,1-b]thiazoles on mitochondrial complex I (NADH-ubiquinone reductase) and on mitochondrial permeability transition pore.

Bioorg. Med. Chem. 12 , 5525-5532, (2004)

In this work we describe the synthesis of a series of imidazo[2,1-b]thiazoles and 2,3-dihydroimidazo[2,1-b]thiazoles connected by means of a methylene bridge to CoQ(0). These compounds were tested as specific inhibitors of the NADH:ubiquinone reductase activi...