5-Nitrofuraldehyde
5-Nitrofuraldehyde structure
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Common Name | 5-Nitrofuraldehyde | ||
|---|---|---|---|---|
| CAS Number | 698-63-5 | Molecular Weight | 141.082 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 252.2±0.0 °C at 760 mmHg | |
| Molecular Formula | C5H3NO4 | Melting Point | 37-39 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 118.6±23.2 °C | |
| Symbol |
GHS02 |
Signal Word | Danger | |
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A selective biomarker for confirming nitrofurazone residues in crab and shrimp using ultra-performance liquid chromatography-tandem mass spectrometry.
Anal. Bioanal. Chem 407 , 8971-7, (2015) Reliably detecting nitrofurazone (NFZ) residues in farmed crab and shrimp was previously hindered by lack of appropriately specific analytical methodology. Parent NFZ rapidly breaks down in meat, and the commonly used side-chain metabolite, semicarbazide (SEM... |
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Conformational stability, vibrational spectra, molecular structure, NBO and HOMO-LUMO analysis of 5-nitro-2-furaldehyde oxime based on DFT calculations.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 104 , 14-25, (2013) The FTIR and FT-Raman spectra of 5-nitro-2-furaldehyde oxime (NFAO) have been recorded in the regions 4000-400 cm(-1) and 3500-50 cm(-1), respectively. The total energies of different conformations have been obtained from DFT (B3LYP) with 6-311++G(d,p) basis ... |
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Design, synthesis, and biological evaluation of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives as potent antitubercular agents.
Bioorg. Med. Chem. Lett. 20 , 6175-8, (2010) Based on stereoelectronic feature analysis using density functional theory (DFT) at B3LYP/3-21∗G level, a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives with low LUMO energies (<-0.10eV); concentrated over the nitro group, furan moiety and α,β-uns... |
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Simultaneous extraction and preconcentration of uranium and thorium in aqueous samples by new modified mesoporous silica prior to inductively coupled plasma optical emission spectrometry determination.
Talanta 80(1) , 212-7, (2009) A new synthesized modified mesoporous silica (MCM-41) using 5-nitro-2-furaldehyde (fural) was applied as an effective sorbent for the solid phase extraction of uranium(VI) and thorium(IV) ions from aqueous solution for the measurement by inductively coupled p... |
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Stability-indicating first-derivative spectrophotometric determination of furazolidone.
Acta Pharm. Hung. 64(1) , 5-8, (1994) A first derivative (1D) spectrophotometric method is described for the determination of furazolidone in the presence of its degradation product (5-nitrofuraldehyde). The method was based on the direct measurement at the maximum of the first derivative curve f... |
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Reactivity of 5-nitro-2-furaldehyde in alkaline and acidic solutions.
Acta Pol. Pharm. 58(6) , 427-34, (2001) 5-Nitro-2-furaldehyde (NFA) forms in alkaline solutions an anion of nitronic acid of (5-nitro-furan-2-yl)-methanediol. Upon acidification (5-nitro-furan-2-yl)-methanediol (HNFA) appears with pKa=4.6. Then, in a novel irreversible redox ring-opening reaction, ... |
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Broad specificity indirect competitive immunoassay for determination of nitrofurans in animal feeds.
Anal. Chim. Acta 678(1) , 1-6, (2010) A generic hapten of nitrofurans was synthesized by derivatization of 5-nitrofurfural with diamine, and the hapten was coupled to carrier protein to prepare different immunogens and coating antigens by using diazotization method and glutaraldehyde method. The ... |
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Formation of methemoglobin by photoactivation of nitrofurantoin or of 5-nitrofurfural in rats exposed to UV-A light.
Toxicology 51(2-3) , 255-66, (1988) The antibacterial drug nitrofurantoin (NFT) is notorious for causing hemolytic anemia, which may be related to the methemoglobinemia, another side-effect of NFT. As NFT is photolabile, and nitrite, well known as a MetHb generator, is an important photoproduct... |
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Cytotoxicity and induction of repairable DNA damage by photoactivated 5-nitrofurfural.
Toxicology 45(1) , 103-12, (1987) 5-Nitrofurfural (NFA) an important photodecomposition product and metabolite of medicinal nitrofurans is phototoxic in bacterial test systems. Its major photodecomposition product 5-hydroxymethylene-2(5H)-furanone (HMF) appears to be responsible for this. Fur... |
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Synthesis and antitrypanosomal evaluation of E-isomers of 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives. structure-activity relationships.
Eur. J. Med. Chem. 35(3) , 343-50, (2000) Several novel semicarbazone derivatives were prepared from 5-nitro-2-furaldehyde or 5-nitrothiophene-2-carboxaldehyde and semicarbazides bearing a spermidine-mimetic moiety. All derivatives presented the E-configuration, as determined by NMR-NOE experiments. ... |