p-Fluoro-β-chloropropiophenone

p-Fluoro-β-chloropropiophenone Structure
p-Fluoro-β-chloropropiophenone structure
Common Name p-Fluoro-β-chloropropiophenone
CAS Number 347-93-3 Molecular Weight 186.611
Density 1.2±0.1 g/cm3 Boiling Point 277.3±20.0 °C at 760 mmHg
Molecular Formula C9H8ClFO Melting Point 47-49 °C(lit.)
MSDS Chinese USA Flash Point 92.2±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Synthesis and pharmacological evaluation of novel arylpiperazine derivatives as nonsteroidal androgen receptor antagonists.

Chem. Pharm. Bull. 52(11) , 1330-3, (2004)

The search for novel antiandrogens by high-throughput screening (HTS) of the Yamanouchi chemical library led to the discovery of the lead compound (5), which possesses an arylmorpholine moiety. Through the optimization of the lead compound (5), we have found ...