J acid

J acid Structure
J acid structure
Common Name J acid
CAS Number 87-02-5 Molecular Weight 239.24800
Density 1.627 g/cm3 Boiling Point N/A
Molecular Formula C10H9NO4S Melting Point N/A
MSDS Chinese USA Flash Point N/A

Transferrin and thyroid hormone converge in the control of myelinogenesis.

Exp. Neurol. 265 , 129-41, (2015)

Myelination is a concerted mechanism tightly regulated in the brain. Although several factors are known to participate during this process, the complete sequence of events is far from being fully elucidated. Separate effects of apotransferrin (aTf) and thyroi...

Successful conversion of the Bacillus subtilis BirA Group II biotin protein ligase into a Group I ligase.

PLoS ONE 9(5) , e96757, (2014)

Group II biotin protein ligases (BPLs) are characterized by the presence of an N-terminal DNA binding domain that allows transcriptional regulation of biotin biosynthetic and transport genes whereas Group I BPLs lack this N-terminal domain. The Bacillus subti...

Free-radical first responders: the characterization of CuZnSOD and MnSOD regulation during freezing of the freeze-tolerant North American wood frog, Rana sylvatica.

Biochim. Biophys. Acta 1850(1) , 97-106, (2014)

The North American wood frog, Rana sylvatica, is able to overcome subzero conditions through overwintering in a frozen state. Freezing imposes ischemic and oxidative stress on cells as a result of cessation of blood flow. Superoxide dismutases (SODs) catalyze...

Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer.

PLoS Genet. 10(10) , e1004751, (2014)

The Notch3 signaling pathway is thought to play a critical role in cancer development, as evidenced by the Notch3 amplification and rearrangement observed in human cancers. However, the molecular mechanism by which Notch3 signaling contributes to tumorigenesi...

Analysis of telomerase activity based on a spired DNA tetrahedron TS primer.

Biosens. Bioelectron. 67 , 364-9, (2015)

The development of sensitive telomerase biosensors is hindered by the restricted accessibility of telomere strand (TS) primer and the limited enzyme reaction space, which is mainly confined by the vertical distance. In this work, we designed an electrochemica...

Efficient and highly sensitive screen for myotonic dystrophy type 1 using a one-step triplet-primed PCR and melting curve assay.

J. Mol. Diagn. 17(2) , 128-35, (2015)

Instability and expansion of the DMPK CTG repeat cause myotonic dystrophy type 1 (DM1), the most common adult-onset neuromuscular disorder. Overlapping clinical features between DM1 and other myotonic disorders necessitate molecular confirmation for definitiv...

Small-molecule xenomycins inhibit all stages of the Plasmodium life cycle.

Antimicrob. Agents Chemother. 59(3) , 1427-34, (2015)

Widespread resistance to most antimalaria drugs in use has prompted the search for novel candidate compounds with activity against Plasmodium asexual blood stages to be developed for treatment. In addition, the current malaria eradication programs require the...

Comparison of responses of DNA topoisomerase I from Candida albicans and human cells to four new agents which stimulate topoisomerase-dependent DNA nicking.

FEMS Microbiol. Lett. 138(2-3) , 105-11, (1996)

DNA topoisomerase I is a potential target for therapeutic antifungal agents predicted to have a fungicidal mode of action. This report describes four agents with varying degrees of selectivity for the fungal topoisomerase I compared to the human enzyme: 5-hyd...

Dysbiosis of gut fungal microbiota is associated with mucosal inflammation in Crohn's disease.

J. Clin. Gastroenterol. 48(6) , 513-23, (2014)

We aim to characterize the fungal microbiota in the intestinal mucosa and feces in patients with Crohn's disease (CD).Fungi represent a diverse microbial community in the human intestine and might play a role in the pathogenesis of CD; however, little is know...

Long-term oral melatonin administration reduces ethanol-induced increases in duodenal mucosal permeability and motility in rats.

Acta Physiol. (Oxf.) 212(2) , 152-65, (2014)

Increased intestinal epithelial permeability is associated with intestinal inflammation and dysfunction. The aim of the present study was to investigate the role of long-term oral melatonin administration on ethanol-induced increases in duodenal mucosal perme...