4-Nitrobenzoyl chloride

4-Nitrobenzoyl chloride Structure
4-Nitrobenzoyl chloride structure
Common Name 4-Nitrobenzoyl chloride
CAS Number 122-04-3 Molecular Weight 185.565
Density 1.5±0.1 g/cm3 Boiling Point 277.8±13.0 °C at 760 mmHg
Molecular Formula C7H4ClNO3 Melting Point 71-74 °C(lit.)
MSDS Chinese USA Flash Point 121.8±19.8 °C
Symbol GHS05
GHS05
Signal Word Danger

Novel benzofuran derivatives for PET imaging of beta-amyloid plaques in Alzheimer's disease brains.

J. Med. Chem. 49(9) , 2725-30, (2006)

A novel series of benzofuran derivatives as potential positron emission tomography (PET) tracers targeting amyloid plaques in Alzheimer's disease (AD) were synthesized and evaluated. The syntheses of benzofurans were successfully achieved by an intramolecular...

Liquid chromatography-mass spectrometric assay of androstenediol in prostatic tissue: influence of androgen deprivation therapy on its level.

Steroids 71(11-12) , 1007-13, (2006)

Androstenediol (Adiol, androst-5-ene-3beta,17beta-diol) is suspected of being an endogenous proliferation agent of prostate cancer (PCa) even after androgen deprivation therapy (ADT). A liquid chromatography-electron capture atmospheric pressure chemical ioni...

[Experimental establishment of the maximum permissible concentration of para-nitrobenzoylchloride in the air of a work area].

Gig. Tr. Prof. Zabol. (9) , 47-8, (1984)

Determination of sugar alcohols in confectioneries by high-performance liquid chromatography after nitrobenzoylation.

J. Chromatogr. A. 893(1) , 195-200, (2000)

A method was developed for the determination of sugar alcohols, meso-erythritol, xylitol, D-glucitol, D-mannitol, maltitol and parachinit by high-performance liquid chromatography (HPLC). The sugar alcohols were converted into strong ultraviolet (UV)-absorbin...

Excretion of glutathione conjugates by primary cultured rat hepatocytes.

J. Biol. Chem. 262(11) , 5151-8, (1987)

Conjugation of xenobiotics with glutathione occurs commonly within the liver, and these glutathione conjugates are then preferentially excreted into bile. We have characterized this excretory process using primary cultured hepatocytes (24 h). 1-Chloro-2,4-din...

Studies on neurosteroids XVIII LC-MS analysis of changes in rat brain and serum testosterone levels induced by immobilization stress and ethanol administration.

Steroids 71(7) , 609-17, (2006)

The liquid chromatography-mass spectrometry (LC-MS) methods were developed and validated for the determination of testosterone (T) in the brain and serum of rats and of 5alpha-androstane-3alpha,17beta-diol (ADIOL), a metabolite of T, in the brain of rats. Aft...

Accidental occupational sensitization to p-nitrobenzoyl chloride in a chemistry student synthesizing procaine.

Contact Dermatitis 20(5) , 397-8, (1989)

A new approach for dynamics of enzyme-catalyzed glutathione conjugation by electrospray quadrupole/time-of-flight mass spectrometry.

Anal. Biochem. 298(1) , 83-92, (2001)

The dynamics of enzyme-catalyzed glutathione conjugation was studied by electrospray quadrupole/time-of-flight (Q-TOF) mass spectrometry with a nanospray interface. After incubation of human glutathione S-transferase A1-1 (GT) with glutathione (GSH) and an el...

Rapid and sensitive high-resolution procedure for digitalis glycoside analysis by derivatization liquid chromatography.

J. Chromatogr. A. 122 , 293, (1976)

The separation and quantitative determination of digitalis glycosides by high performance liquid chromatography following derivatization with 4-nitrobenzoylchloride (4-NBC1) is described. The compounds of primary interest were the digitalis glycosides and agl...

Ruben Vardanyan, Victor Hruby

Synthesis of Essential Drugs , (2006), 391