Oxymetholone
Oxymetholone structure
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Common Name | Oxymetholone | ||
|---|---|---|---|---|
| CAS Number | 434-07-1 | Molecular Weight | 332.477 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 465.9±45.0 °C at 760 mmHg | |
| Molecular Formula | C21H32O3 | Melting Point | 172-180°C | |
| MSDS | Chinese USA | Flash Point | 249.7±25.2 °C | |
| Symbol |
GHS08 |
Signal Word | Warning | |
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Detection of urinary metabolites common to structurally related 17alpha-alkyl anabolic steroids in horses and application to doping tests in racehorses: methandienone, methandriol, and oxymetholone.
J. Anal. Toxicol. 32(5) , 387-91, (2008) Methandienone, methandriol, and oxymetholone, which are anabolic steroids possessing 17alpha-methyl and 17beta-hydroxy groups, were developed as oral formulations for therapeutic purposes. However, they have been used in racehorses to enhance racing performan... |
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Hepatocellular adenomas associated with anabolic androgenic steroid abuse in bodybuilders: a report of two cases and a review of the literature.
Br. J. Sports Med. 39(5) , e27, (2005) Anabolic androgenic steroids (AAS) are used illicitly at high doses by bodybuilders. The misuse of these drugs is associated with serious adverse effects to the liver, including cellular adenomas and adenocarcinomas. We report two very different cases of adul... |
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Characterization of spontaneous and chemically induced cardiac lesions in rodent model systems: the national toxicology program experience.
Cardiovasc. Toxicol. 5(2) , 227-44, (2005) Induction of heart disease can be related to exposure to a number of agents, including environmental chemicals. Studies with laboratory rodents are commonly used to identify cardiotoxic agents and to investigate mechanisms of toxicity. This study was conducte... |
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Direct and indirect effects of androgens on survival of hematopoietic progenitor cells in vitro.
J. Korean Med. Sci. 20(3) , 409-16, (2005) Androgens remain a common treatment for certain type of anemia, based upon its myelostimulating effects; however, it has not been established whether androgens affect apoptosis of hematopoietic progenitor cells (HPCs). We investigated the effects of the andro... |
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Morphologic aspects of rodent cardiotoxicity in a retrospective evaluation of National Toxicology Program studies.
Toxicol. Pathol. 39(5) , 850-60, (2011) The heart is increasingly recognized as a target for toxicity. As studies in laboratory rodents are commonly used to investigate the potential toxicity of various agents, the identification and characterization of lesions of cardiotoxicity is of utmost import... |
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Oral oxymetholone reduces mortality induced by gamma irradiation in mice through stimulation of hematopoietic cells.
Mol. Cell Biochem. 287(1-2) , 193-9, (2006) Oxymetholone is a 17alpha -alkylated anabolic-androgenic steroid. This drug can stimulate bone marrow cells and increase the blood cells in the peripheral blood vessels. It has been used for the treatment of anemia caused by low red cell production. Since oxy... |
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Improvement in erythropoieis-stimulating agent-induced pure red-cell aplasia by introduction of darbepoetin-α when the anti-erythropoietin antibody titer declines spontaneously.
J. Korean Med. Sci. 25(11) , 1676-9, (2010) Anti-erythropoietin antibodies usually cross-react with all kinds of recombinant erythropoietins; therefore, erythropoiesis-stimulating agent (ESA)-induced pure red-cell aplasia (PRCA) is not rescued by different ESAs. Here, we present a case of ESA-induced P... |
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Clinical course of non-severe aplastic anemia in adults.
Int. J. Hematol. 91(5) , 770-5, (2010) The clinical course of non-severe aplastic anemia is variable, and risk factors related to disease progression are not well known. We reviewed clinical and laboratory data of the patients who were diagnosed with non-severe aplastic anemia from 1997 to 2007 at... |
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The efficacy of oxymetholone in combination with erythropoietin on hematologic parameters and muscle mass in CAPD patients.
Int. J. Clin. Pharmacol. Ther. 48(12) , 803-13, (2010) To determine the efficacy of oxymetholone, an androgenic steroid, in combination with rHuEPO on hematologic and muscle mass in CAPD patients.A double-blinded, placebo-controlled experimental study was conducted for 6 months and 24 CAPD patients were divided i... |
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Clonal monosomy 7 in a megakaryoblastic leukemia developed on the basis of Fanconi anemia.
J. Pediatr. Hematol. Oncol. 27(10) , 565-6, (2005) A 13-year-old girl with a history of Fanconi anemia developed acute myeloid leukemia of the M7 subtype with a 45,XX,-7 karyotype, which is rare in M7 subtype. Treatment protocols were set up, but she died of sepsis and osteomyelitis during induction. |