Estazolam

Estazolam Structure
Estazolam structure
Common Name Estazolam
CAS Number 29975-16-4 Molecular Weight 294.73800
Density 1.4 g/cm3 Boiling Point 489.9ºCat 760 mmHg
Molecular Formula C16H11ClN4 Melting Point 228.5ºC
MSDS USA Flash Point 11 °C
Symbol GHS07
GHS07
Signal Word Warning

A quick method for determination of psychoactive agents in serum and hair by using capillary electrophoresis and mass spectrometry.

J. Pharm. Biomed. Anal. 111 , 177-85, (2015)

The aim of the research was to develop a new sensitive method for simultaneously the determination of psychoactive drugs: 1-benzylpiperazine, 7-aminoclonazepam, alprazolam, clonazepam, diazepam, estazolam, lorazepam and tetrazepam in human serum and hair samp...

[Simultaneous determination of 5 sedative hypnotics in human plasma by reversed phase high-performance liquid chromatography].

Zhong Nan Da Xue Xue Bao. Yi Xue Ban 34(7) , 689-92, (2009)

To determine diazepam, nitrazepam, oxazepam, estazolam, and alprazolam simultaneously in human plasma by reversed phase high-performance liquid chromatography (RP-HPLC).Ten microliter carbamazepine (50 mg/L)as the internal standard was added into 1 mL sample,...

Long-term stability of various drugs and metabolites in urine, and preventive measures against their decomposition with special attention to filtration sterilization.

Forensic Sci. Int. 174(2-3) , 189-96, (2008)

The long-term stability of drugs and metabolites of forensic interest in urine, and preventive measures against their decomposition have been investigated, with special attention to filtration sterilization. An aseptic urine collection kit, which was recently...

Identification and quantification of 34 drugs and toxic compounds in blood, urine, and gastric content using liquid chromatography with tandem mass spectrometry.

J. Sep. Sci. 38 , 1680-90, (2015)

A liquid chromatography with tandem mass spectrometry method was developed for the simultaneous screening of 34 drugs and poisons in forensic cases. Blood (0.5 mL, diluted 1:1 with water) or 1.0 mL of urine was purified by solid-phase extraction. Gastric cont...

Development and validation of an LC-MS/MS method for the simultaneous analysis of 28 specific narcotic adulterants used in dietary supplements.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 32 , 1029-39, (2015)

The purpose of this study was to develop a method to analyse the concentration of multiple illegal narcotics present in dietary supplements. To this end, we established and optimised a procedure using LC-MS/MS simultaneously to analyse 28 narcotic compounds i...

[Determination of 10 sedative-hypnotics in human plasma using pulse splitless injection technique and gas chromatography-mass spectrometry].

Se Pu 29(11) , 1082-6, (2011)

A simple, precise and sensitive gas chromatography-mass spectrometry (GC-MS) method coupled with pulse splitless injection technique was developed for the determination of 10 sedative-hypnotics (barbital, amobarbital, phenobarbital, oxazepam, diazepam, nitraz...

Mapping intrinsic functional brain changes and repetitive transcranial magnetic stimulation neuromodulation in idiopathic restless legs syndrome: a resting-state functional magnetic resonance imaging study.

Sleep Med. 16 , 785-91, (2015)

The objectives of this study were, first, to explore differences in brain activity between normal people and idiopathic restless legs syndrome (RLS) patients during asymptomatic periods; and, second, to determine whether administering repetitive transcranial ...

Treatment of phlegm- and heat-induced insomnia by acupuncture in 120 cases.

J. Tradit. Chin. Med. 23(1) , 57-8, (2003)

[Identification of estazolam, alprazolam and triazolam in human urine by LC/MSn].

Yao Xue Xue Bao 37(2) , 138-40, (2002)

To investigate the fragmentation behavior of triazolobenzodiazepines and to develop a specific, sensitive and rapid LC/MSn assay for simultaneous determination of estazolam, alprazolam and triazolam in human urine.After oral administration of a single 4 mg do...

[Two complex suicidal poisonings with drugs and their medicolegal aspects].

Prz. Lek. 58(4) , 344-7, (2001)

The main subject of the study was a toxicological investigation of biological specimens coming from two cases of intoxication with mixture of drugs. Two young people decided to commit suicide by the use of mixture of drugs mainly analgesic in approximately eq...