2-Phenyl-1H-imidazole

2-Phenyl-1H-imidazole Structure
2-Phenyl-1H-imidazole structure
Common Name 2-Phenyl-1H-imidazole
CAS Number 670-96-2 Molecular Weight 144.173
Density 1.1±0.1 g/cm3 Boiling Point 340.0±11.0 °C at 760 mmHg
Molecular Formula C9H8N2 Melting Point 142-148 °C(lit.)
MSDS Chinese USA Flash Point 180.4±5.7 °C
Symbol GHS07
GHS07
Signal Word Warning

Preparation, physicochemical characterization and pharmacological study of novel ruthenium(III) complexes with imidazole and benzimidazole derivatives.

Arzneimittelforschung 51(9) , 758-62, (2001)

Complex compounds of ruthenium(III) with 1,2-dimethylimidazole (CAS 1739-84-0), 2-phenylimidazole (CAS 670-96-2) and 2-aminobenzimidazole (CAS 934-32-7) were prepared and were characterised by physicochemical methods. Coordination sites were determined. The c...

Calmodulin-dependent nitric-oxide synthase. Mechanism of inhibition by imidazole and phenylimidazoles.

J. Biol. Chem. 268(13) , 9425-9, (1993)

Calmodulin-dependent nitric-oxide synthase from bovine brain and GH3 pituitary cells is inhibited by imidazole, 1-phenylimidazole, 2-phenylimidazole, and 4-phenylimidazole, with half-maximal inhibition occurring at 200, 25, 160, and 600 microM concentrations ...

Bindings of axial ligands to cytochrome P-450d mutants: a difference absorption spectral study.

Biochim. Biophys. Acta 995(2) , 116-21, (1989)

By site-directed mutagenesis, we made several cytochrome P-450d (P-450d) mutants as follows: Asn310Phe (D13), Ile312Leu (D14), Glu318Asp (D15), Val320Ile (D16), Phe325Thr (D19), Asn310Phe,Ile312Leu (M6), Glu318Asp,Val320Ile (M7), Phe325Thr, Glu318Asp (M3). Th...

Ligand binding studies of engineered cytochrome P-450d wild type, proximal mutants, and distal mutants.

Biochemistry 30(6) , 1490-6, (1991)

Interactions of various axial ligands with cytochrome P-450d wild type, proximal mutants (Lys453Glu, Ile460Ser), and putative distal mutants (Glu318Asp, Thr319Ala, Thr322Ala) expressed in yeast were studied with optical absorption spectroscopy. P-450d wild ty...

Substituent effects on enthalpies of formation of nitrogen heterocycles: 2-substituted benzimidazoles and related compounds.

J. Phys. Chem. A 110(7) , 2535-44, (2006)

The enthalpies of combustion, heat capacities, enthalpies of sublimation and enthalpies of formation of 2-tert-butylbenzimidazole (2tBuBIM) and 2-phenylimidazole (2PhIM) are reported and the results compared with those of benzene derivatives and a series of a...

Exploring selectivity requirements for peripheral versus central benzodiazepine receptor binding affinity: QSAR modeling of 2-phenylimidazo[1,2-a]pyridine acetamides using topological and physicochemical descriptors.

Indian J. Biochem. Biophys. 43(2) , 105-18, (2006)

Considering the potential of peripheral benzodiazepine receptor (PBR) ligands in therapeutic applications and clinical benefit in the management of a large spectrum of different indications, quantitative structure-activity relationship (QSAR) study has been a...