5-Isopropyl-2-methylphenol
5-Isopropyl-2-methylphenol structure
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Common Name | 5-Isopropyl-2-methylphenol | ||
|---|---|---|---|---|
| CAS Number | 499-75-2 | Molecular Weight | 150.218 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 237.2±9.0 °C at 760 mmHg | |
| Molecular Formula | C10H14O | Melting Point | 3-4 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 106.7±0.0 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Evidence for the involvement of descending pain-inhibitory mechanisms in the attenuation of cancer pain by carvacrol aided through a docking study.
Life Sci. 116(1) , 8-15, (2014) The present study evaluated the carvacrol (CARV) effect on hyperalgesia and nociception induced by sarcoma 180 (S180) in mice.Carvacrol treatment (12.5-50mg/kgs.c.) once daily for 15days was started 24h after injection of the sarcoma cells in the hind paw (s.... |
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Comparison of biological processes induced in HepG2 cells by tert-butyl hydroperoxide (t-BHP) and hydroperoxide (H2O2): The influence of carvacrol.
Mutat. Res. 757(1) , 15-22, (2013) This paper presents comparisons of biological impacts of the oxidants H2O2 and t-BHP on human liver cells, and shows modulation of these effects by the phenolic compound carvacrol. To understand better how these oxidants exert their effect on DNA and on the a... |
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Activity of essential oil of Lippia triplinervis Gardner (Verbenaceae) on Rhipicephalus microplus (Acari: Ixodidae).
Parasitol. Res. 112(2) , 863-9, (2013) The objective of this work was to characterize and investigate the acaricidal activity of the essential oil of the aerial parts of Lippia triplinervis at different concentrations on unengorged larvae and engorged females of Rhipicephalus microplus. The essent... |
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Activation of human 5-hydroxytryptamine type 3 receptors via an allosteric transmembrane site.
Mol. Pharmacol. 87(1) , 87-95, (2015) In common with other members of the Cys-loop family of pentameric ligand-gated ion channels, 5-hydroxytryptamine type 3 receptors (5-HT3Rs) are activated by the binding of a neurotransmitter to an extracellular orthosteric site, located at the interface of tw... |
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Supplemental carvacrol can reduce the severity of inflammation by influencing the production of mediators of inflammation.
Inflammation 38 , 1020-7, (2015) Carvacrol (CVC) is a monoterpenic phenol, which is present in the essential oil of various plants. It has been widely used both as antibacterial feed additive and food preservative. Therefore, our objective was to evaluate the prophylactic effects of carvacro... |
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Effect of carvacrol on tracheal responsiveness, inflammatory mediators, total and differential WBC count in blood of sensitized guinea pigs.
Exp. Biol. Med. (Maywood.) 238(2) , 200-8, (2013) The effects of carvacrol on tracheal responsiveness (TR) to methacholine and ovalbumin (OA), serum nitric oxide (NO) concentration, total and differential white blood cells (WBC) in blood of sensitized guinea pigs were examined. Five groups of guinea pigs sen... |
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Expanding the ChemGPS chemical space with natural products.
J. Nat. Prod. 68 , 985-91, (2005) Recently various attempts have been made to increase the efficacy and precision of chemical libraries used in high-throughput screening (HTS) drug discovery approaches. One such approach is ChemGPS, which provides a defined chemical space for prescreening eva... |
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Rapid inactivation of Salmonella Enteritidis on shell eggs by plant-derived antimicrobials.
Poult. Sci. 92(12) , 3228-35, (2013) Salmonella Enteritidis is a common foodborne pathogen transmitted to humans largely by consumption of contaminated eggs. The external surface of eggs becomes contaminated with Salmonella Enteritidis from various sources on farms, the main sources being hens' ... |
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Downregulation of yidC in Escherichia coli by antisense RNA expression results in sensitization to antibacterial essential oils eugenol and carvacrol.
PLoS ONE 8(3) , e57370, (2013) The rising drug resistance in pathogenic bacteria and inefficiency of current antibiotics to meet clinical requirements has augmented the need to establish new and innovative approaches for antibacterial drug discovery involving identification of novel antiba... |
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Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
J. Med. Chem. 53 , 5085-107, (2010)
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