Chlortetracycline
Chlortetracycline structure
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Common Name | Chlortetracycline | ||
|---|---|---|---|---|
| CAS Number | 57-62-5 | Molecular Weight | 478.880 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 821.1±65.0 °C at 760 mmHg | |
| Molecular Formula | C22H23ClN2O8 | Melting Point | 168.5ºC | |
| MSDS | Chinese USA | Flash Point | 450.4±34.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Metagenome-wide association of microbial determinants of host phenotype in Drosophila melanogaster.
MBio 5(5) , e01631-14, (2014) Animal-associated bacteria (microbiota) affect host behaviors and physiological traits. To identify bacterial genetic determinants of microbiota-responsive host traits, we employed a metagenome-wide association (MGWA) approach in two steps. First, we measured... |
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Photolysis of chlortetracycline in aqueous solution: kinetics, toxicity and products.
J. Environ. Sci. (China) 24(2) , 254-60, (2012) The aqueous photodegradation of the widely used antibiotic chlortetracycline (CTC) was investigated under simulated sunlight. The quantum yield of photodegradation increased from 3.3 x 10(-4) to 8.5 x 10(-3) within the pH range of 6.0 to 9.0. The presence of ... |
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Validation of Polo-like kinase 1 as a therapeutic target in pancreatic cancer cells.
Cancer Biol. Ther. 13(12) , 1214-20, (2012) Polo-like kinase 1 (PLK1) is a serine/threonine protein kinase and plays a critical role in mitosis. PLK1 has also been regarded as a valuable target for cancer treatment, and several PLK1 inhibitors are currently undergoing clinical investigations. In this s... |
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Differential regulation of OmpC and OmpF by AtpB in Escherichia coli exposed to nalidixic acid and chlortetracycline.
J. Proteomics 75(18) , 5898-910, (2012) Little is known about mechanisms through which OmpR/EnvZ and CpxA/CpxR regulate the expression of OmpC and OmpF, and thereby regulate bacterial responses to antibiotics exposure. In this study we investigated the relationships among OmpC, OmpF and TCSs using ... |
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Determination on the binding of chlortetracycline to bovine serum albumin using spectroscopic methods.
J. Biochem. Mol. Toxicol. 26(9) , 331-6, (2012) In this work, the interaction of chlortetracycline with bovine serum albumin (BSA) was investigated by fluorescence spectroscopy, circular dichroism (CD) spectroscopy, and molecular docking. Results indicated that chlortetracycline quenches BSA fluorescence m... |
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Development and validation of a liquid chromatographic/ tandem mass spectrometric method for determination of chlortetracycline, oxytetracycline, tetracycline, and doxycycline in animal feeds.
J. AOAC Int. 95(4) , 1010-5, (2012) A selective and accurate LC/MS/MS method for the simultaneous determination of chlortetracycline (CTC), oxytetracycline (OTC), tetracycline (TC), and doxycycline (DC) in animal feeds was developed. Samples were extracted with Na2EDTA-McIlvaine buffer and furt... |
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Chlortetracycline degradation by photocatalytic ozonation in the aqueous phase: mineralization and the effects on biodegradability.
Environ. Technol. 34(1-4) , 495-502, (2013) Chlortetracycline (CTC) is a hazardous material in aquatic environments. This study was focused on optimization of photocatalytic ozonation processes for removal of CTC from wastewater at pH 2.2 and 7.0. In this study, the tested processes for CTC removal wer... |
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Competitive effect of commensal faecal bacteria from growing swine fed chlortetracycline-supplemented feed on β-haemolytic Escherichia coli strains with multiple antimicrobial resistance plasmids.
J. Appl. Microbiol. 113(3) , 659-68, (2012) To determine the differences in competitive fitness among Escherichia coli strains with different plasmid profiles when grown in suspension with commensal faecal bacteria from growing swine fed chlortetracycline-supplemented or unsupplemented diets.Five multi... |
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Biochemical effects of veterinary antibiotics on proliferation and cell cycle arrest of human HEK293 cells.
Bull. Environ. Contam. Toxicol. 89(2) , 234-9, (2012) The purpose of this study was to examine the effects of veterinary antibiotics, including amoxicillin (AMX), chlortetracycline (CTC) and tylosin (TYL), on the biochemical mechanism of human embryonic kidney cells (HEK293). CTC and TYL inhibited HEK293 cell pr... |
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In vitro development and transfer of resistance to chlortetracycline in Bacillus subtilis.
J. Microbiol. 50(5) , 807-12, (2012) The present criteria and rules controlling the approval of the use of probiotics are limited to antibiotic resistance patterns and the presence of antibiotic resistance genes in bacteria. There is little information available in the literature regarding the r... |