m-PEG24-amine
m-PEG24-amine structure
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Common Name | m-PEG24-amine | ||
|---|---|---|---|---|
| CAS Number | 32130-27-1 | Molecular Weight | 61.08310 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C2H7NO | Melting Point | N/A | |
| MSDS | USA | Flash Point | 278ºC | |
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Particles without a box: brush-first synthesis of photodegradable PEG star polymers under ambient conditions.
J. Vis. Exp. (80) , doi:10.3791/50874, (2013) Convenient methods for the rapid, parallel synthesis of diversely functionalized nanoparticles will enable discovery of novel formulations for drug delivery, biological imaging, and supported catalysis. In this report, we demonstrate parallel synthesis of bru... |
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Drug-loaded, bivalent-bottle-brush polymers by graft-through ROMP.
Macromolecules 43 , 10326-10335, (2010) Graft-through ring-opening metathesis polymerization (ROMP) using ruthenium N-heterocyclic carbene catalysts has enabled the synthesis of bottle-brush polymers with unprecedented ease and control. Here we report the first bivalent-brush polymers; these materi... |
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Core-clickable PEG-branch-azide bivalent-bottle-brush polymers by ROMP: grafting-through and clicking-to.
J. Am. Chem. Soc. 133 , 559-566, (2011) The combination of highly efficient polymerizations with modular "click" coupling reactions has enabled the synthesis of a wide variety of novel nanoscopic structures. Here we demonstrate the facile synthesis of a new class of clickable, branched nanostructur... |
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Redox-responsive branched-bottlebrush polymers for in vivo MRI and fluorescence imaging.
Nat. Commun. 5 , 5460, (2014) Stimuli-responsive multimodality imaging agents have broad potential in medical diagnostics. Herein, we report the development of a new class of branched-bottlebrush polymer dual-modality organic radical contrast agents--ORCAFluors--for combined magnetic reso... |
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Synthesis of Acid-Labile PEG and PEG-Doxorubicin-Conjugate Nanoparticles via Brush-First ROMP.
ACS Macro Lett. 3(9) , 854-857, (2014) A panel of acid-labile bis-norbornene cross-linkers was synthesized and evaluated for the formation of acid-degradable brush-arm star polymers (BASPs) via the brush-first ring-opening metathesis polymerization (ROMP) method. An acetal-based cross-linker was i... |
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A convergent synthetic platform for single-nanoparticle combination cancer therapy: ratiometric loading and controlled release of cisplatin, doxorubicin, and camptothecin.
J. Am. Chem. Soc. 136(16) , 5896-9, (2014) The synthesis of polymer therapeutics capable of controlled loading and synchronized release of multiple therapeutic agents remains a formidable challenge in drug delivery and synthetic polymer chemistry. Herein, we report the synthesis of polymer nanoparticl... |
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Brush-first synthesis of core-photodegradable miktoarm star polymers via ROMP: towards photoresponsive self-assemblies.
Macromol. Rapid Commun. 35(2) , 168-73, (2014) This report describes the synthesis of miktoarm brush-arm star polymers (BASPs) from branched and linear norbornene-terminated macromonomers (MMs) via the brush-first ring-opening metathesis polymerization (ROMP) method. First, a polystyrene (PS)-branch-poly(... |
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Brush-first and click: efficient synthesis of nanoparticles that degrade and release doxorubicin in response to light.
Photochem. Photobiol. 90(2) , 380-5, (2014) New strategies for the synthesis of multifunctional particles that respond to external stimuli and release biologically relevant agents will enable the discovery of new formulations for drug delivery. In this article, we combine two powerful methods: brush-fi... |