esatenolol

esatenolol Structure
esatenolol structure
Common Name esatenolol
CAS Number 93379-54-5 Molecular Weight 266.33600
Density 1.125 g/cm3 Boiling Point 508ºC at 760mmHg
Molecular Formula C14H22N2O3 Melting Point 148-152 ºC(lit.)
MSDS USA Flash Point 261.1ºC

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ...

Effects of nebivolol on endothelial gene expression during oxidative stress in human umbilical vein endothelial cells.

Mediators Inflamm. 2008 , 367590, (2008)

The endothelium plays a key role in the development of atherogenesis and its inflammatory and proliferative status influences the progression of atherosclerosis. The aim of this study is to compare the effects of two beta blockers such as nebivolol and atenol...

The effects of (+/-)-, (+)-, and (-)-atenolol, sotalol, and amosulalol on the rat left atria and portal vein.

Chirality 5 , 8-14, (1993)

The effects of (+/-)-, (+)-, and (-)-atenolol, sotalol, and amosulalol alone on the rat left atria and portal vein and on the respective beta 1- and beta 2-adrenoceptor-mediated responses to isoprenaline have been determined. (+/-)-Atenolol at 10(-6) M had no...

Molecular Dynamics Simulation and NMR Investigation of the Association of the _-Blockers Atenolol and Propranolol with a Chiral Molecular Micelle.

Chem. Phys. 457 , 133-146, (2015)

Molecular dynamics simulations and NMR spectroscopy were used to compare the binding of two _-blocker drugs to the chiral molecular micelle poly-(sodium undecyl-(L)-leucine-valine). The molecular micelle is used as a chiral selector in capillary electrophores...

A stereoselective central hypotensive action of atenolol.

J. Pharmacol. Exp. Ther. 250 , 759-763, (1989)

Previous studies have demonstrated that propranolol can lower arterial pressure through an action within the central nervous system. The purpose of this study was to determine 1) whether the hydrophilic beta blocking drug atenolol which is devoid of membrane ...