β-Estradiol 17-acetate
β-Estradiol 17-acetate structure
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Common Name | β-Estradiol 17-acetate | ||
|---|---|---|---|---|
| CAS Number | 1743-60-8 | Molecular Weight | 314.41900 | |
| Density | 1.18g/cm3 | Boiling Point | 450.5ºC at 760 mmHg | |
| Molecular Formula | C20H26O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 181.9ºC | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats.
J. Neuroimmunol. , (2008) Estrogen has been shown to attenuate the inflammatory response following injury or lipopolysaccharide treatment in several organ systems. Estrogen's actions are transduced through two estrogen receptor sub-types, estrogen receptor (ER) -alpha and estrogen rec... |
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LCAT facilitates transacylation of 17 beta-estradiol in the presence of HDL3 subfraction.
J. Lipid Res. 43(3) , 392-7, (2002) It has been shown that estrogens need to be metabolized to their hydrophobic estrogen ester derivatives to act as antioxidants in lipoproteins. Data suggest that 17beta-estradiol (E(2)) becomes esterified in LCAT-induced reactions and the esters are transport... |
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High-performance liquid chromatographic determination of 17beta-estradiol and 17beta-estradiol-3-acetate solubilities and diffusion coefficents in silicone elastromeric intravaginal rings.
J. Chromatogr. B. Biomed. Sci. Appl. 744(1) , 157-63, (2000) A rapid, sensitive reversed-phase high-performance liquid chromatographic method has been developed for the determination of in vitro release of 17beta-estradiol and its ester prodrug, 17beta-estradiol-3-acetate, from silicone intravaginal rings. Partial hydr... |
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The influence of 17-beta-estradiol 17-beta-acetate on adenylyl cyclase activity and aminoacyl-tRNA synthetase phosphatase activity in ovariectomized NMRI mice.
Biochem. Int. 24(3) , 527-33, (1991) Adenylyl cyclase activity in the uterus of ovariectomized NMRI mice showed an increase of 87% four minutes after intraperitoneal administration of 17-beta-estradiol 17-beta-acetate in water solution, while in the liver of the same animals activity had decreas... |
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Reversal of the effect of 17-beta-estradiol 17-beta-acetate on aminoacyl-tRNA synthetase phosphatase and aminoacyl-tRNA synthetase activities in the uterus and liver of ovariectomized Bom:NMRI mice by 2-deoxyadenosine 3-phosphate.
Biochem. Mol. Biol. Int. 29(5) , 959-64, (1993) When an adenylyl cyclase inhibitor, 2-deoxyadenosine 3'-phosphate, was administered together with 17-beta-estradiol 17-beta-acetate on ovariectomized Bom:NMRI mice, the short term effects of the hormone on the uterus aminoacyl-tRNA synthetase phosphatase and ... |
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Comparison of skin distribution of hydrolytic activity for bioconversion of beta-estradiol 17-acetate between man and several animals in vitro.
Eur. J. Pharm. Biopharm. 54(2) , 155-60, (2002) We have investigated the distribution of hydrolytic enzymes which metabolize beta-estradiol 17-acetate (EA) to beta-estradiol (E) in man and animal skins in vitro. The distribution of hydrolytic enzymes in human cadaver, hairless dog, rat and hairless mouse s... |
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Estrogen increases hair pigmentation in female recessive yellow mice.
Zoolog. Sci. 27(6) , 470-6, (2010) Murine recessive yellow (Mc1r(e)) is a loss-of-function mutation in the receptor for alpha-melanocyte-stimulating hormone, melanocortin receptor 1 (Mc1r), and results in a yellow coat by inducing pheomelanin synthesis in hair follicular melanocytes. We previo... |