AS-604850

AS-604850 Structure
AS-604850 structure
Common Name AS-604850
CAS Number 648449-76-7 Molecular Weight 285.224
Density 1.7±0.1 g/cm3 Boiling Point N/A
Molecular Formula C11H5F2NO4S Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

Nat. Med. 11 , 936-943, (2005)

Phosphoinositide 3-kinases (PI3K) have long been considered promising drug targets for the treatment of inflammatory and autoimmune disorders as well as cancer and cardiovascular diseases. But the lack of specificity, isoform selectivity and poor biopharmaceu...