PALGLY
PALGLY structure
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Common Name | PALGLY | ||
|---|---|---|---|---|
| CAS Number | 2441-41-0 | Molecular Weight | 313.48 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 491.8±28.0 °C at 760 mmHg | |
| Molecular Formula | C18H35NO3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 251.2±24.0 °C | |
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¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.
PLoS ONE 10(3) , e0120950, (2015) Curcumin, a principle bioactive component of Curcuma longa L, is well known for its anti-hyperlipidemia effect. However, no holistic metabolic information of curcumin on hyperlipidemia models has been revealed, which may provide us an insight into the underly... |
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GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.
PLoS ONE 8 , e60314, (2013) The G-protein coupled receptor 55 (GPR55) is activated by lysophosphatidylinositols and some cannabinoids. Recent studies found prominent roles for GPR55 in neuropathic/inflammatory pain, cancer and bone physiology. However, little is known about the role of ... |
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Glycine N-acyltransferase-like 3 is responsible for long-chain N-acylglycine formation in N18TG2 cells.
J. Lipid Res. 57 , 781-90, (2016) Long-chain fatty acid amides are signaling lipids found in mammals and other organisms; however, details of the metabolic pathways for the N-acylglycines and primary fatty acid amides (PFAMs) have remained elusive. Heavy-labeled precursor and subtraction lipi... |
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Effects of feeding Spodoptera littoralis on lima bean leaves. I. Membrane potentials, intracellular calcium variations, oral secretions, and regurgitate components.
Plant Physiol. 134(4) , 1752-62, (2004) Membrane potentials (V(m)) and intracellular calcium variations were studied in Lima bean (Phaseolus lunatus) leaves when the Mediterranean climbing cutworm (Spodoptera littoralis) was attacking the plants. In addition to the effect of the feeding insect the ... |
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[Pharmacologic profile of n-palmitoylglycine. Its effect on reserpine and haloperidol catalepsy].
Boll. Chim. Farm. 134(5) , 258-62, (1995) N-palmitoyl glycine (PG), synthesized by the mixed anhydrides method, displayed nootropic effects (in the "step-down" test) as well as an anti-immobility action in the forced swimming test, in mice. However no anticonvulsant effects were obtained, even at hig... |
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Novel endogenous N-acyl glycines identification and characterization.
Vitam. Horm. 81 , 191-205, (2009) Discovery of the endogenous cannabinoid and N-acyl amide, anandamide (N-arachidonoyl ethanolamine), paved the way for lipidomics discoveries in the growing family of N-acyl amides. Lipidomics is a field that is broadening our view of the molecular world to in... |
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Conformational equilibrium of cytochrome P450 BM-3 complexed with N-palmitoylglycine: a replica exchange molecular dynamics study.
J. Am. Chem. Soc. 128(17) , 5786-91, (2006) UV-vis absorbance measurements and associated studies of cytochrome P450 BM-3 in complex with N-palmitoylglycine (NPG) indicate that a conformational change occurs in the active site of the complex where the terminal atoms of the ligand move from a site dista... |
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Pivotal role of water in the mechanism of P450BM-3.
Biochemistry 40(45) , 13456-65, (2001) Cytochrome P450s constitute a superfamily of enzymes that catalyze the oxidation of a vast number of structurally and chemically diverse hydrophobic substrates. Herein, we describe the crystal structure of a complex between the bacterial P450BM-3 and the nove... |
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Conformational dynamics of substrate in the active site of cytochrome P450 BM-3/NPG complex: insights from NMR order parameters.
J. Am. Chem. Soc. 129(3) , 474-5, (2007)
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Opportunistic activation of TRP receptors by endogenous lipids: exploiting lipidomics to understand TRP receptor cellular communication.
Life Sci. 92(8-9) , 404-9, (2013) Transient receptor potential channels (TRPs) form a large family of ubiquitous non-selective cation channels that function as cellular sensors and in many cases regulate intracellular calcium. Identification of the endogenous ligands that activate these TRP r... |