PALGLY
PALGLY structure
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Common Name | PALGLY | ||
|---|---|---|---|---|
| CAS Number | 2441-41-0 | Molecular Weight | 313.48 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 491.8±28.0 °C at 760 mmHg | |
| Molecular Formula | C18H35NO3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 251.2±24.0 °C | |
Use of PALGLYPalmitoylglycine, a novel endogenous lipid, acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Palmitoylglycine induces transient influx of calcium followed by nitric oxide production via calcium-sensitive nitric-oxide synthase enzymes. Palmitoylglycine potently inhibits heat-evoked firing of nociceptive neurons in rat dorsal horn[1]. |
| Name | 2-(hexadecanoylamino)acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Palmitoylglycine, a novel endogenous lipid, acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Palmitoylglycine induces transient influx of calcium followed by nitric oxide production via calcium-sensitive nitric-oxide synthase enzymes. Palmitoylglycine potently inhibits heat-evoked firing of nociceptive neurons in rat dorsal horn[1]. |
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| Related Catalog | |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 491.8±28.0 °C at 760 mmHg |
| Molecular Formula | C18H35NO3 |
| Molecular Weight | 313.48 |
| Flash Point | 251.2±24.0 °C |
| Exact Mass | 313.261688 |
| PSA | 66.40000 |
| LogP | 6.03 |
| Appearance of Characters | white to off-white |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.468 |
| InChIKey | KVTFEOAKFFQCCX-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCCC(=O)NCC(=O)O |
| Storage condition | 2-8°C |
| Water Solubility | DMSO: >10mg/mL |
| Personal Protective Equipment | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2924199090 |
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~76%
PALGLY CAS#:2441-41-0 |
| Literature: McIlhinney; Harvey Journal of Mass Spectrometry, 1995 , vol. 30, # 6 p. 900 - 910 |
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PALGLY CAS#:2441-41-0 |
| Literature: Dang, Hung The; Kang, Gyeoung Jin; Yoo, Eun Sook; Hong, Jongki; Choi, Jae Sue; Kim, Hyung Sik; Chung, Hae Young; Jung, Jee H. Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 4 p. 1520 - 1527 |
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PALGLY CAS#:2441-41-0 |
| Literature: Duarte, Rodrigo Da Costa; Ongaratto, Renata; Piovesan, Luciana Almeida; De Lima, Vania Rodrigues; Soldi, Valdir; Merlo, Aloir Antonio; D'Oca, Marcelo G. Montes Tetrahedron Letters, 2012 , vol. 53, # 19 p. 2454 - 2460 |
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PALGLY CAS#:2441-41-0 |
| Literature: Bondi; Frankl Biochemische Zeitschrift, 1909 , vol. 17, p. 552 |
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Detail
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| Literature: Conopco, Inc., d/b/a UNILEVER Patent: US2007/299269 A1, 2007 ; Location in patent: Page/Page column 5-6; 7 ; |
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PALGLY CAS#:2441-41-0 |
| Literature: Iyer, Venkataraman N.; Sheth, Geeta N.; Subrahmanyam, V. V. R. Journal of the Indian Chemical Society, 1982 , vol. 59, # 7 p. 856 - 859 |
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PALGLY CAS#:2441-41-0 |
| Literature: KYUSHU UNIVERSITY; NISSAN CHEMICAL INDUSTRIES, LTD. Patent: US2012/35108 A1, 2012 ; |
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PALGLY CAS#:2441-41-0 |
| Literature: Duarte, Rodrigo Da Costa; Ongaratto, Renata; Piovesan, Luciana Almeida; De Lima, Vania Rodrigues; Soldi, Valdir; Merlo, Aloir Antonio; D'Oca, Marcelo G. Montes Tetrahedron Letters, 2012 , vol. 53, # 19 p. 2454 - 2460 |
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~%
PALGLY CAS#:2441-41-0 |
| Literature: Abderhalden; Funk Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1910 , vol. 65, p. 66 |
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.
PLoS ONE 10(3) , e0120950, (2015) Curcumin, a principle bioactive component of Curcuma longa L, is well known for its anti-hyperlipidemia effect. However, no holistic metabolic information of curcumin on hyperlipidemia models has been... |
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GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.
PLoS ONE 8 , e60314, (2013) The G-protein coupled receptor 55 (GPR55) is activated by lysophosphatidylinositols and some cannabinoids. Recent studies found prominent roles for GPR55 in neuropathic/inflammatory pain, cancer and b... |
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Glycine N-acyltransferase-like 3 is responsible for long-chain N-acylglycine formation in N18TG2 cells.
J. Lipid Res. 57 , 781-90, (2016) Long-chain fatty acid amides are signaling lipids found in mammals and other organisms; however, details of the metabolic pathways for the N-acylglycines and primary fatty acid amides (PFAMs) have rem... |
| N-Ethanoyl-Hexadecanamide |
| PALGLY |
| N-hexadecanoyl glycine |
| Palmitoylglycine |
| QV1MV15 |
| N-palmitatoylglycyne |
| N-(1-Oxohexadecyl)glycine |
| N-Hexadecanoylglycine |
| Glycine, N-(1-oxohexadecyl)- |
| Hexadecanoylaminoacetic acid N-palmitoyl glycine |
| Hexadecanoylaminoacetic acid,N-palmitoyl glycine |
| 2-(Hexadecanoylamino)acetic acid |
| N-palmitoyl glycine |
| N-Palmitoylglycine |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: PALGLY
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- Purity: 98.0%
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: PALMITOYL GLYCINE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
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- Zhongshan Xingrui Chemical Co. , Ltd.
- China
- Product Name: PALGLY
- Price: ￥Inquiry/25kg
- Purity: 99.0%
- Delivery: Inquiry
- Contact: Wang Jie
- Email: 3096638339@qq.com
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