DL-threo-PDMP (hydrochloride)
DL-threo-PDMP (hydrochloride) structure
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Common Name | DL-threo-PDMP (hydrochloride) | ||
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| CAS Number | 80938-69-8 | Molecular Weight | 427.020 | |
| Density | N/A | Boiling Point | 607.4ºC at 760 mmHg | |
| Molecular Formula | C23H39ClN2O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 321.2ºC | |
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Effects of D-threo-PDMP, an inhibitor of glucosylceramide synthetase, on expression of cell surface glycolipid antigen and binding to adhesive proteins by B16 melanoma cells.
J. Cell Physiol. 141 , 573-583, (1989) Incubating B16 melanoma cells with an inhibitor of glucosylceramide (GlcCer) synthetase, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-threo-PDMP), led to a considerable decrease in the levels of GlcCer and lactosylceramide (LacCer). The content... |
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Inhibition of glycosphingolipid synthesis by threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) and the modulation of IL-1beta-stimulated expression of inducible nitric oxide synthase in rat aortic smooth muscle cells.
Br. J. Pharmacol. 123 , 906-910, (1998) 1. The composition of glycosphingolipids is altered in atherosclerotic tissue. In order to study the possible modulation of interleukin-1beta (IL-1beta)-induced expression of inducible nitric oxide synthase (iNOS) by endogenously synthesized glycosphingolipid... |
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Radin, et al.
J. Lipid Res. 26 , 183-213, (1993)
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