DL-threo-PDMP (hydrochloride)
Modify Date: 2024-01-02 22:37:28
DL-threo-PDMP (hydrochloride) structure
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Common Name | DL-threo-PDMP (hydrochloride) | ||
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| CAS Number | 80938-69-8 | Molecular Weight | 427.020 | |
| Density | N/A | Boiling Point | 607.4ºC at 760 mmHg | |
| Molecular Formula | C23H39ClN2O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 321.2ºC | |
Use of DL-threo-PDMP (hydrochloride)DL-threo-PDMP inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates when used at concentrations of 5 and 10 M. |
| Name | DL-threo-PDMP (hydrochloride) |
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| Synonym | More Synonyms |
| Boiling Point | 607.4ºC at 760 mmHg |
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| Molecular Formula | C23H39ClN2O3 |
| Molecular Weight | 427.020 |
| Flash Point | 321.2ºC |
| Exact Mass | 426.264923 |
| PSA | 61.80000 |
| LogP | 4.80850 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
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Effects of D-threo-PDMP, an inhibitor of glucosylceramide synthetase, on expression of cell surface glycolipid antigen and binding to adhesive proteins by B16 melanoma cells.
J. Cell Physiol. 141 , 573-583, (1989) Incubating B16 melanoma cells with an inhibitor of glucosylceramide (GlcCer) synthetase, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-threo-PDMP), led to a considerable decrease in the ... |
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Inhibition of glycosphingolipid synthesis by threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) and the modulation of IL-1beta-stimulated expression of inducible nitric oxide synthase in rat aortic smooth muscle cells.
Br. J. Pharmacol. 123 , 906-910, (1998) 1. The composition of glycosphingolipids is altered in atherosclerotic tissue. In order to study the possible modulation of interleukin-1beta (IL-1beta)-induced expression of inducible nitric oxide sy... |
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Radin, et al.
J. Lipid Res. 26 , 183-213, (1993)
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| d,l-threo-pdmp hcl |
| N-[(1R,2R)-1-Hydroxy-3-(4-morpholinyl)-1-phenyl-2-propanyl]decanamide hydrochloride (1:1) |
| dl-pdmp |
| pdmp hydrochloride glucosylceramide sy nthase inhibitor |
| 1-phenyl-2-decanoylamino-3-morpholino-1-propanol,hcl |
| dl-threo-pdmp,hydrochloride |
| Decanamide, N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-, hydrochloride (1:1) |