Lithium 3-oxobutanoate
Lithium 3-oxobutanoate structure
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Common Name | Lithium 3-oxobutanoate | ||
|---|---|---|---|---|
| CAS Number | 3483-11-2 | Molecular Weight | 108.022 | |
| Density | 1.182g/cm3 | Boiling Point | 237.7ºC at 760mmHg | |
| Molecular Formula | C4H5LiO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 111.8ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Hyperketonemia induces upregulation of LFA-1 in monocytes, which is mediated by ROS and P38 MAPK activation.
Can. J. Physiol. Pharmacol. 90(12) , 1642-6, (2012) Type 1 diabetic patients have hyperketonemia, elevated levels of pro-inflammatory and oxidative stress markers, and a higher incidence of vascular disease. This study examines the hypothesis that hyperketonemia increases reactive oxygen species (ROS) and is i... |
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Stimulation of mild, sustained ketonemia by medium-chain triacylglycerols in healthy humans: estimated potential contribution to brain energy metabolism.
Nutrition 29(4) , 635-40, (2013) In humans consuming a normal diet, we investigated 1) the capacity of a medium-chain triacylglycerol (MCT) supplement to stimulate and sustain ketonemia, 2) ¹³C-β-hydroxybutyrate and ¹³C-trioctanoate metabolism, and 3) the theoretical contribution of the degr... |
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Use of hyperpolarized [1-13C]pyruvate and [2-13C]pyruvate to probe the effects of the anticancer agent dichloroacetate on mitochondrial metabolism in vivo in the normal rat.
Magn. Reson. Imaging 30(10) , 1367-72, (2012) Development of hyperpolarized technology utilizing dynamic nuclear polarization has enabled the measurement of (13)C metabolism in vivo at very high signal-to-noise ratio (SNR). In vivo mitochondrial metabolism can, in principle, be monitored with pyruvate, w... |
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Elevated acetoacetate and monocyte chemotactic protein-1 levels in cord blood of infants of diabetic mothers.
Neonatology 102(3) , 163-8, (2012) Infants of diabetic mothers (IDMs) are at increased risk for metabolic complications. Type 1 and some type 2 diabetic patients have elevated levels of the ketone bodies acetoacetate (AA) and β-hydroxybutyrate (BHB).The aim of this study was to examine how hyp... |
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Hepatic expression of cytochrome P450 in type 2 diabetic Goto-Kakizaki rats.
Chem. Biol. Interact. 195(3) , 173-9, (2012) Although hepatic expression of cytochrome P450 (CYP) changes markedly in diabetes, the role of ketone bodies in the regulation of CYP in diabetes is controversial. The present study was performed to determine the expression and activity of CYP in non-obese ty... |
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Control of selectivity in the generation and reactions of oxonium ylides.
Chem. Commun. (Camb.) 47(27) , 7623-5, (2011) Dirhodium catalyzed reactions of aryl-substituted tetrahydropyranone diazoacetoacetates produce ylide intermediates that unexpectedly yield two oxabicyclo[4.2.1]-nonane diastereoisomers, but a single diastereoisomer is formed by increasing the steric bulk of ... |
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Acute exposure to the mitochondrial complex I toxin rotenone impairs synaptic long-term potentiation in rat hippocampal slices.
CNS Neurosci. Ther. 18(8) , 641-6, (2012) To evaluate the acute effects of the mitochondrial complex I inhibitor rotenone on rat hippocampal synaptic plasticity.Electrophysiological field potential recordings were used to measure basal synaptic transmission and synaptic plasticity in rat coronal hipp... |
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Regulation of the Escherichia coli AtoSC two component system by synthetic biologically active 5;7;8-trimethyl-1;4-benzoxazine analogues.
Bioorg. Med. Chem. 19(16) , 5061-70, (2011) The Escherichia coli AtoSC two component system;upon acetoacetate induction;regulates the expression of the atoDAEB operon;through His→Asp phopshotransfer;thus modulating important cellular processes. In this report the effect of seven 5,7,8-trimethyl-1,4-ben... |
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Nitrate-dependent degradation of acetone by Alicycliphilus and Paracoccus strains and comparison of acetone carboxylase enzymes.
Appl. Environ. Microbiol. 77(19) , 6821-5, (2011) A novel acetone-degrading, nitrate-reducing bacterium, strain KN Bun08, was isolated from an enrichment culture with butanone and nitrate as the sole sources of carbon and energy. The cells were motile short rods, 0.5 to 1 by 1 to 2 μm in size, which gave Gra... |
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1H NMR-based metabonomic analysis of metabolic changes in streptozotocin-induced diabetic rats.
Anal. Sci. 26(12) , 1277-82, (2010) Diabetes mellitus is a complex metabolic disorder characterized by chronic hyperglycemia, hypoinsulinemia, and ketosis. To access the biochemical process of diabetes, we applied quantitative (1)H NMR-based metabonomics to analyze urine, serum, and liver extra... |