UNII:88I7UKE7IM
UNII:88I7UKE7IM structure
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Common Name | UNII:88I7UKE7IM | ||
|---|---|---|---|---|
| CAS Number | 616-23-9 | Molecular Weight | 128.985 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 184.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C3H6Cl2O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 98.5±15.8 °C | |
| Symbol |
GHS05, GHS06 |
Signal Word | Danger | |
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Mechanism of chemical activation of sodium chloride in the presence of amino acids.
Food Chem. 166 , 301-8, (2014) Sodium chloride has been shown to promote chlorination of glycerol during thermal processing. However, the detailed mechanism of this reaction is not well understood. Preliminary experiments have indicated that the reaction mixture should contain an amino aci... |
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The simultaneous separation and determination of chloropropanols in soy sauce and other flavoring with gas chromatography-mass spectrometry in negative chemical and electron impact ionization modes.
Food Addit. Contam. 23(2) , 110-9, (2006) Both gas chromatography-mass spectrometry in electron ionization (GC-MS-EI) and negative chemical ionization (GC-MS-NCI) modes are reported in this paper for the simultaneous determination of 1,3-dichloropropan-2-ol (1,3-DCP), 2,3-dichloropropan-1-ol (2,3-DCP... |
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Directed evolution strategies for enantiocomplementary haloalkane dehalogenases: from chemical waste to enantiopure building blocks.
ChemBioChem. 13(1) , 137-48, (2012) We used directed evolution to obtain enantiocomplementary haloalkane dehalogenase variants that convert the toxic waste compound 1,2,3-trichloropropane (TCP) into highly enantioenriched (R)- or (S)-2,3-dichloropropan-1-ol, which can easily be converted into o... |
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Haloalcohols deplete glutathione when incubated with fortified liver fractions.
Xenobiotica 29(5) , 533-45, (1999) 1. This study has examined the ability of dichloropropanols, haloalcohols and their putative metabolites to deplete glutathione when incubated with liver fractions obtained from untreated and differentially induced rats. 2. 1,3-Dichloropropan-2-ol and 2,3-dic... |
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Effect of cyanamide on toxicity and glutathione depletion in rat hepatocyte cultures: differences between two dichloropropanol isomers.
Chem. Biol. Interact. 122(2) , 107-15, (1999) The effect of aldehyde dehydrogenase inhibition by cyanamide pre-treatment in vitro on dichloropropanol-dependent toxicity and glutathione depletion was investigated in 24 h rat hepatocyte cultures. Cyanamide pre-treatment had no effect on nitrophenol hydroxy... |
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A study of the conformational stability and the vibrational spectra of 2,3-dichloro-1-propanol.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 75(2) , 734-8, (2010) The conformational stability and the three rotor internal rotations in 2,3-dichloro-1-propanol were investigated at DFT-B3LYP/6-311+G**, MP2/6-311+G** and MP4(SDQ) levels of theory. From the calculated potential energy surface, ten distinct minima were locate... |
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Enhancement of (S)-2,3-dichloro-1-propanol production by recombinant whole-cell biocatalyst in n-heptane-aqueous biphasic system.
J. Biotechnol. 188C , 42-47, (2014) The enantioselective resolution of (R,S)-2,3-dichloro-1-propanol ((R,S)-DCP) to (S)-DCP by whole cells of a recombinant Escherichia coli expressing halohydrin dehalogenase (HHDH) activity was limited by product inhibition. To solve this problem to improve the... |
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The inhibition of 2,3-dichloro-1-propanol on T cell in vitro and in vivo.
Int. Immunopharmacol. 17(2) , 321-8, (2013) 2,3-Dichloro-1-propanol (2,3-DCP) is a member of a group of chemicals known as chloropropanols. Currently, immunotoxicity of 2,3-DCP has not been reported. In the present study, we studied its inhibitory effects on T cell both in vivo and in vitro. The result... |
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Novel dehalogenase mechanism for 2,3-dichloro-1-propanol utilization in Pseudomonas putida strain MC4.
Appl. Environ. Microbiol. 78(17) , 6128-36, (2012) A Pseudomonas putida strain (MC4) that can utilize 2,3-dichloro-1-propanol (DCP) and several aliphatic haloacids and haloalcohols as sole carbon and energy source for growth was isolated from contaminated soil. Degradation of DCP was found to start with oxida... |
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On-line coupling of equilibrium-sorptive enrichment to gas chromatography to determine low-molecular-mass pollutants in environmental water samples.
J. Chromatogr. A. 867(1-2) , 207-18, (2000) On-line combination of equilibrium sorptive enrichment and gas chromatography is used for the analysis of a group of pollutants varying widely in polarity and volatility in aqueous samples at trace levels. For the ESE process open-tubular traps were used. The... |