Oxythiamine chloride hydrochloride
Oxythiamine chloride hydrochloride structure
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Common Name | Oxythiamine chloride hydrochloride | ||
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| CAS Number | 614-05-1 | Molecular Weight | 351.25200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H16Cl2N4O2S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Inhibition of protein phosphorylation in MIA pancreatic cancer cells: confluence of metabolic and signaling pathways.
J. Proteome Res. 9 , 980-989, (2010) Oxythiamine (OT), a transketolase inhibitor, is known to inhibit pancreatic cancer cell proliferation. In this study, we investigated the effect of inhibition of the transketolase pathway on signaling pathways in MIA PaCa cancer cells using in-house proteomic... |
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The in vitro and in vivo anti-metastatic efficacy of oxythiamine and the possible mechanisms of action.
Clin. Exp. Metastasis 27 , 341-349, (2010) This study examined the anti-metastatic effects of oxythiamine (OT) both in cell culture and in vivo. Cell culture results revealed that OT (0-20 microM) significantly inhibited the invasion and migration (IC(50) = 8.75 microM) of Lewis lung carcinoma (LLC) c... |
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