D-erythro-Neopterin
D-erythro-Neopterin structure
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Common Name | D-erythro-Neopterin | ||
|---|---|---|---|---|
| CAS Number | 2009-64-5 | Molecular Weight | 253.215 | |
| Density | 2.0±0.1 g/cm3 | Boiling Point | 697.7ºC at 760mmHg | |
| Molecular Formula | C9H11N5O4 | Melting Point | >232ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | 375.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Increased serum levels of quinolinic acid indicate enhanced severity of hepatic dysfunction in patients with liver cirrhosis.
Hum. Immunol. 74(1) , 60-6, (2013) The Model for End-Stage Liver Disease (MELD) score is a tool for assessment of the degree of hepatic insufficiency/failure. Quinolinic acid (QuinA) is a tryptophan metabolite produced by activated macrophages. Here we investigate whether the degree of systemi... |
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A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study.
Clin. Exp. Immunol. 173(1) , 121-30, (2013) Circulating neopterin and kynurenine/tryptophan ratio (KTR) increase during inflammation and serve as markers of cellular immune activation, but data are sparse on other determinants of these markers and metabolites of the kynurenine pathway. We measured neop... |
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Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study.
Clin. Exp. Immunol. 176(3) , 452-60, (2014) The risk of osteoporosis increases in inflammatory disorders. In cell-mediated immune activation, interferon (IFN)-γ stimulates macrophage release of neopterin and increases the activity of indoleamine 2,3-dioxygenase (IDO), thereby stimulating tryptophan deg... |
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[Peculiarities of the circulating phagocytes functional activity in patients with different forms of drug-resistant pulmonary tuberculosis].
Biomed. Khim. 58(4) , 467-74, (2012) Functional activity of circulating phagocytes (macrophages--Ms and neutrophils--Ns) was studied in 30 patients with infiltrative (I) and 30 patients with fibro-cavernous (FC) pulmonary tuberculosis (PT). Difference of the functional activity of both types of ... |
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Oxidative stress and inflammation in lean and obese subjects with polycystic ovary syndrome.
J. Reprod. Med. 58(3-4) , 107-14, (2013) To determine whether polycystic ovary syndrome (PCOS) independently influences oxidative stress and inflammation or if the culprit is the comorbidities of obesity and/or insulin resistance common to this condition.Thirty women with PCOS were matched for age, ... |
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Nimesulide may be more efficient than allopurinol in protecting pancreas from acute ischemia/reperfusion injury in an animal model.
Vasc. Endovascular Surg. 46(8) , 654-63, (2012) To determine the influence of allopurinol and nimesulide in the protection of the pancreas from acute ischemia-reperfusion (I/R) injury.A total of 30 rabbits were divided into 3 groups, group A: acute I/R only; group B: allopurinol (30 mg/kg) was administered... |
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Serum levels of neopterin during antimicrobial treatment for Mycobacterium ulcerans infection.
Am. J. Trop. Med. Hyg. 89(3) , 498-500, (2013) Neopterin is closely associated with activation of the cellular immune system. Neopterin levels differed between controls and patients with Buruli ulcer disease. No differences between patients with or without paradoxical responses were observed. Therefore, n... |
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A sexual risk and stress reduction intervention designed for HIV-positive bisexual African American men with childhood sexual abuse histories.
Am. J. Public Health 103(8) , 1476-84, (2013) HIV transmission risk is high among men who have sex with men and women (MSMW), and it is further heightened by a history of childhood sexual abuse (CSA) and current traumatic stress or depression. Yet, traumatic stress is rarely addressed in HIV intervention... |
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Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolate.
ACS Chem. Biol. 7(11) , 1807-16, (2012) C-1 carriers are essential cofactors in all domains of life, and in Archaea, these can be derivatives of tetrahydromethanopterin (H(4)-MPT) or tetrahydrofolate (H(4)-folate). Their synthesis requires 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) as t... |
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Increased levels of serum neopterin in attention deficit/hyperactivity disorder (ADHD).
J. Neuroimmunol. 273(1-2) , 111-4, (2014) Attention deficit/hyperactivity disorder (ADHD) is the most frequently occurring neuropsychiatric disorder in childhood with an etiology that is not fully understood. A number of reviews that have addressed the neurobiology of ADHD have focused on imaging and... |