Sodium bisulfite
Sodium bisulfite structure
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Common Name | Sodium bisulfite | ||
|---|---|---|---|---|
| CAS Number | 7631-90-5 | Molecular Weight | 104.061 | |
| Density | 1.48 | Boiling Point | N/A | |
| Molecular Formula | NaHSO3 | Melting Point | 150 °C | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition.
Nucleic Acids Res. 43(1) , 162-78, (2015) The loss of the tumour suppressor E-cadherin (Cdh1) is a key event during tumourigenesis and epithelial-mesenchymal transition (EMT). Transforming growth factor-β (TGFβ) triggers EMT by inducing the expression of non-histone chromatin protein High Mobility Gr... |
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Purification and inhibition studies with anions and sulfonamides of an α-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii.
Bioorg. Med. Chem. 19 , 1847-51, (2011) A high activity α-carbonic anhydrase (CA, EC 4.2.1.1) has been purified from various tissues of the Antarctic seal Leptonychotes weddellii. The new enzyme, denominated lwCA, has a catalytic activity for the physiologic CO(2) hydration to bicarbonate reaction,... |
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Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.
Nat. Commun. 5 , 5582, (2014) Solid tumours are exposed to microenvironmental factors such as hypoxia that normally inhibit cell growth. However, tumour cells are capable of counteracting these signals through mechanisms that are largely unknown. Here we show that the prolyl hydroxylase P... |
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Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogenSalmonella entericaserovar Typhimurium
Bioorg. Med. Chem. Lett. 21 , 3591-5, (2011) Two new β-carbonic anhydrases (CAs, EC 4.2.1.1) from the bacterial pathogen Salmonella enterica serovar Typhimurium, stCA 1 and stCA 2, were characterized kinetically. The two enzymes possess appreciable activity as catalysts for the hydration of CO(2) to bic... |
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Anion inhibition studies of an α-carbonic anhydrase from the living fossil Astrosclera willeyana.
Bioorg. Med. Chem. Lett. 22 , 1314-6, (2012) An α-carbonic anhydrase (CA, EC 4.2.1.1) isolated from the living fossil sponge Astrosclera willeyana, Astrosclerin, was investigated for its inhibition profile with simple inorganic anions, complex anions and other small molecules known to interact with thes... |
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Subtelomeric demethylation deregulated hTERT expression, telomerase activity, and telomere length in four nasopharyngeal carcinoma cell lines.
Cancer Biother. Radiopharm. 29(7) , 289-94, (2014) Global DNA hypomethylation, in particular that of the gene promoter sequence in gene hypermethylation, is a well-known characteristic of human cancer. Subtelomeres are enriched CpG islands; methylation is believed to be a potential epigenetic regulator. Howev... |
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Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis.
Neuro. Oncol. 17(1) , 63-9, (2014) Malignant peripheral nerve sheath tumor (MPNST) is a rare and highly aggressive disease with no evidence of effect from adjuvant therapy. It is further associated with the hereditary syndrome neurofibromatosis type 1 (NF1). Silencing of the tumor suppressor g... |
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Microsatellite instability, promoter methylation and protein expression of the DNA mismatch repair genes in epithelial ovarian cancer.
Genomics 104(4) , 257-63, (2014) The role of defective mismatch repair (MMR) system in ovarian carcinoma is not well defined. The purpose of the study was to determine the relationship between microsatellite instability (MSI), promoter methylation and protein expression of MMR genes in epith... |
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DNA methylation and expression of KCNQ3 in bipolar disorder.
Bipolar Disord. 17(2) , 150-9, (2015) Accumulating evidence implicates the potassium voltage-gated channel, KQT-like subfamily, member 2 and 3 (KCNQ2 and KCNQ3) genes in the etiology of bipolar disorder (BPD). Reduced KCNQ2 or KCNQ3 gene expression might lead to a loss of inhibitory M-current and... |
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Identification of HERC5 and its potential role in NSCLC progression.
Int. J. Cancer 136(10) , 2264-72, (2015) For better lung cancer diagnosis and therapy, early detection markers of tumor dissemination are urgently needed, as most lung cancers do not show symptoms until extensive metastasis formation has already taken place. Our previous studies showed that in non-s... |